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  5. Methyl carbazole-3-carboxylate

Methyl carbazole-3-carboxylate 

目录号: HY-N3288 纯度: 98.10%
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Mmethylcarbodium-3-carboxylate 是一种可从 Clausena lansium (Lour.) Skeels 的果皮中分离出来的咔唑生物碱。

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Methyl carbazole-3-carboxylate Chemical Structure

Methyl carbazole-3-carboxylate Chemical Structure

CAS No. : 97931-41-4

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Methylcarbazole-3-carboxylate is a carbazole alkaloid can be isolated from the peel of Clausena lansium (Lour.) Skeels[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HepG2 IC50
36.9 μM
Compound: 5
Growth inhibition of human HepG2 cells after 48 hrs by WST-8 based CCK8 assay
Growth inhibition of human HepG2 cells after 48 hrs by WST-8 based CCK8 assay
[PMID: 22093759]
KB IC50
59.7 μM
Compound: 18
Cytotoxicity against human KB cells by resazurin reduction assay
Cytotoxicity against human KB cells by resazurin reduction assay
[PMID: 22482432]
MCF7 IC50
169.8 μM
Compound: 18
Cytotoxicity against human MCF7 cells by resazurin reduction assay
Cytotoxicity against human MCF7 cells by resazurin reduction assay
[PMID: 22482432]
NCI-H187 IC50
95.8 μM
Compound: 18
Cytotoxicity against human NCI-H187 cells by resazurin reduction assay
Cytotoxicity against human NCI-H187 cells by resazurin reduction assay
[PMID: 22482432]
Neutrophil IC50
> 10 μM
Compound: 20
Antiinflammatory activity in human neutrophil assessed as inhibition of FMLP/CB-induced elastase release for 5 mins
Antiinflammatory activity in human neutrophil assessed as inhibition of FMLP/CB-induced elastase release for 5 mins
[PMID: 24798144]
Neutrophil IC50
4.3 μM
Compound: 20
Antiinflammatory activity in human neutrophil assessed as inhibition of FMLP/CB-induced superoxide anion generation pretreated for 5 mins by spectrophotometry
Antiinflammatory activity in human neutrophil assessed as inhibition of FMLP/CB-induced superoxide anion generation pretreated for 5 mins by spectrophotometry
[PMID: 24798144]
分子量

225.24

Formula

C14H11NO2

CAS 号
性状

固体

颜色

Light brown to brown

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
溶解性数据
细胞实验: 

DMSO 中的溶解度 : 125 mg/mL (554.96 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响,请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 4.4397 mL 22.1985 mL 44.3971 mL
5 mM 0.8879 mL 4.4397 mL 8.8794 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 2 years; -20°C, 1 year。-80°C储存时,请在2年内使用,-20°C储存时,请在1年内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 2 years; -20°C, 1 year。-80°C储存时,请在2年内使用,-20°C储存时,请在1年内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.4397 mL 22.1985 mL 44.3971 mL 110.9927 mL
5 mM 0.8879 mL 4.4397 mL 8.8794 mL 22.1985 mL
10 mM 0.4440 mL 2.2199 mL 4.4397 mL 11.0993 mL
15 mM 0.2960 mL 1.4799 mL 2.9598 mL 7.3995 mL
20 mM 0.2220 mL 1.1099 mL 2.2199 mL 5.5496 mL
25 mM 0.1776 mL 0.8879 mL 1.7759 mL 4.4397 mL
30 mM 0.1480 mL 0.7400 mL 1.4799 mL 3.6998 mL
40 mM 0.1110 mL 0.5550 mL 1.1099 mL 2.7748 mL
50 mM 0.0888 mL 0.4440 mL 0.8879 mL 2.2199 mL
60 mM 0.0740 mL 0.3700 mL 0.7400 mL 1.8499 mL
80 mM 0.0555 mL 0.2775 mL 0.5550 mL 1.3874 mL
100 mM 0.0444 mL 0.2220 mL 0.4440 mL 1.1099 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Methyl carbazole-3-carboxylate
目录号:
HY-N3288
需求量: