2. Mimopezil

Mimopezil (ZT-1) 是一种胆碱酯酶抑制剂，在水或水溶性有机溶剂中会迅速降解为活性代谢物 Huperzine A (HY-17388)。Mimopezil 口服后吸收迅速但生物利用度低 (0.37%，大鼠)，但代谢后转化为 Huperzine A，Huperzine A 在血液中积累并具有较强的活性。静脉给药后 Mimopezil 血药浓度较高，同样迅速代谢为 Huperzine A。

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Mimopezil Chemical Structure

Mimopezil Chemical Structure

CAS No. : 180694-97-7

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Mimopezil 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Mimopezil (ZT-1) is an cholinesterase (ChE) inhibitor that rapidly degrades into the active metabolite Huperzine A (HY-17388) in water or aqueous organic solvents. After oral administration, Mimopezil is rapidly absorbed but has low bioavailability (0.37%) in rats. However, after metabolism, it is converted into Huperzine A, which accumulates in the blood and exhibits strong activity. Following intravenous administration, Mimopezil reaches higher blood concentrations and is also rapidly metabolized into Huperzine A[1].

分子量

410.89

Formula

C23H23ClN2O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Mimopezil 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mimopezil180694-97-7ZT-1ZT1ZT 1Inhibitorinhibitorinhibit

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目录号：
HY-14795
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