1. Anti-infection
  2. Parasite
  3. MMV688533

MMV688533 是一种抗疟剂,具有快速的抗疟原虫活性,在人源化小鼠模型中具有有效的单剂量抗恶性疟原虫感染活性。MMV688533 能抑制无性血期寄生虫的活性,IC50 值为 1.3 nM。MMV688533 具有良好的药代动力学特性和安全性。

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MMV688533 Chemical Structure

MMV688533 Chemical Structure

CAS No. : 2260904-47-8

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规格 价格 是否有货 数量
1 mg ¥2100
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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MMV688533 is an antimalarial agent with rapid anti-plasmodial activity and effective single-dose activity against Plasmodium falciparum infection in humanized mouse models. MMV688533 can inhibit the activity of asexual blood stage parasites with an IC50 value of 1.3 nM. MMV688533 exhibits excellent pharmacokinetic properties and safety[1].

分子量

519.40

Formula

C24H15F6N5O2

CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献

MMV688533 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
MMV688533
目录号:
HY-148178
需求量: