2. MAPK/ERK Pathway
  3. MNK
  4. MNK inhibitor 9

MNK inhibitor 9 是一种有效的选择性的 MNK1/2 抑制剂， IC50 值分别为 0.003 µM 和 0.003 µM。MNK inhibitor 9 具有良好的细胞渗透性。MNK inhibitor 9 可用于肿瘤相关研究。

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MNK inhibitor 9 Chemical Structure

MNK inhibitor 9 Chemical Structure

CAS No. : 1889336-59-7

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规格 价格 是否有货 数量
1 mg ￥2500
3 - 5 周
5 mg 现货 3 - 5 周
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MNK inhibitor 9 相关抗体

Top Publications Citing Use of Products

查看 MNK 亚型特异性产品:

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MNK1 MNK2 MNK

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MNK inhibitor 9 is a potent and selective inhibitor of MNK1/2 with IC50 values of 0.003 µM and 0.003 µM for MNK1 and MNK2 respectively. MNK inhibitor 9 has good cell permeability. MNK inhibitor 9 can be used in tumor related research[1].

IC50 & Target[1]

MNK1

0.003 μM (IC50)

MNK2

0.003 μM (IC50)

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
KMS-11 EC50
1.7 μM
Compound: 9
Antiproliferative activity against luciferase expressing human KMS11 cells after 5 days by CellTiter-Glo luminescent assay
Antiproliferative activity against luciferase expressing human KMS11 cells after 5 days by CellTiter-Glo luminescent assay
[PMID: 27002243]
体外研究
(In Vitro)

MNK inhibitor 9 (Compound 9) 抑制 CaMK2D、FLT3、PIM2 和 ROCK2 的活性，IC50 分别为 0.69 µM、0.28 µM、0.73 µM 和 0.37 µM[1]。
MNK inhibitor 9 抑制 KMS11-luc 人多发性骨髓瘤肿瘤细胞系的增值，EC50 值为 1.7 µM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

MNK inhibitor 9 相关抗体:
分子量

471.56

Formula

C25H29N9O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

MNK inhibitor 9 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MNK inhibitor 91889336-59-7MNK inhibitor9MNK inhibitor-9MNKMitogen activated protein kinase interacting kinaseMAP kinase interacting kinaseMAPK interacting kinaseCaMK2DFLT3PIM2ROCK2KMS11-lucInhibitorinhibitorinhibit

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