1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. NAD Synthetase

NAD Synthetase  (Synonyms: NAD+ Synthetase; Nicotinamide adenine dinucleotide synthetase)

目录号: HY-E70410
产品使用指南

NAD Synthetase 负责烟酰胺腺嘌呤二核苷酸 (NAD) 合成的最后一步。来源于大肠杆菌的 NAD synthetase 对 NAD、ATP 及氨的 Km 值分别为 200,11 和 0.65 μM,来源于酵母的 NAD synthetase 对 NAD、ATP 及氨的 Km 值分别为 170,190 和 64 μM。NAD Synthetase 可用于ATP、氨、尿素或肌酐的酶促测定,也可用于酶促循环法。同时 NAD Synthetase 有望用于代谢疾病、癌症、衰老和神经退行性疾病研究。

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NAD Synthetase Chemical Structure

NAD Synthetase Chemical Structure

CAS No. : 9032-69-3

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生物活性

NAD synthetase is responsible for the final step in the synthesis of nicotinamide adenine dinucleotide (NAD). The Km values for NAD, ATP, and ammonia of NAD synthetase from Escherichia coli are 200 μM, 11 μM, and 0.65 μM, respectively, while the Km values for NAD, ATP, and ammonia of NAD synthetase from yeast are 170 μM, 190 μM, and 64 μM, respectively. NAD synthetase can be used for enzymatic assays to determine ATP, ammonia, urea, or creatinine, and is also suitable for enzymatic cycling methods. Additionally, NAD synthetase holds potential for research into metabolic diseases, cancer, aging, and neurodegenerative diseases[1][2].

CAS 号
中文名称

NAD合成酶

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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