2. Immunology/Inflammation
  3. NO Synthase
  4. NOS-IN-1

NOS-IN-1 是一种有效的具有口服活性的一氧化氮合酶 (NOS) 的抑制剂，对人 iNOS (hiNOS)，heNOS 和 hnNOS 的 IC50 分别为 0.1 μM，1.1 μM 和 0.2 μM。

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NOS-IN-1 Chemical Structure

NOS-IN-1 Chemical Structure

CAS No. : 165383-72-2

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规格 价格 是否有货 数量
1 mg ￥714
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NOS-IN-1 相关抗体

Top Publications Citing Use of Products

查看 NO Synthase 亚型特异性产品:

查看所有亚型
nNOS iNOS eNOS

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

NOS-IN-1 is a potent and orally active NO synthase (NOS) isoforms inhibitor with IC50s of 0.1 μM, 1.1 μM, and 0.2 μM for human iNOS (hiNOS), heNOS and hnNOS, respectively[1].

IC50 & Target

IC50: 0.1 μM (hiNOS), 1.1 μM (heNOS), and 0.2 μM (hnNOS)[1]
体内研究
(In Vivo)

Following oral administration, NOS-IN-1 (compound 3; 10 mg/kg) decreases serum nitrite/nitrate levels in an in vivo rat endotoxin assay[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

172.22

Formula

C8H16N2O2
CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

纯度 & 产品资料
参考文献

NOS-IN-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NOS-IN-1165383-72-2NO SynthaseNitric oxide synthasesNOSiNOSeNOSnNOSoralnitritenitrateInhibitorinhibitorinhibit

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产品名称：
NOS-IN-1
目录号：
HY-138564
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