2. Neuronal Signaling
  3. Cholinesterase (ChE)
  4. Obidoxime dichloride

Obidoxime dichloride 

目录号: HY-W011108 纯度: 96.60%
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Obidoxime dichloride 是一种非全谱肟试剂，可作为有机磷类神经毒剂中毒的解毒剂。Obidoxime dichloride 可活化被沙林蛋白抑制的乙酰胆碱酯酶 (AChE)，降低沙林蛋白的急性毒性。

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Obidoxime dichloride Chemical Structure

Obidoxime dichloride Chemical Structure

CAS No. : 114-90-9

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5 mg ￥936
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Obidoxime dichloride 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Obidoxime dichloride is a non-full spectrum oxime agent and can be used as an antidote for organophosphate nerve agent poisoning. Obidoxime dichloride reactivates sarin-inhibited acetylcholinesterase (AChE) and reduces acute toxicity of sarin-evaluated[1].

体内研究
(In Vivo)

Obidoxime dichloride (intramuscular injection; 10 mg/kg; after 60 mins) exhibits a LD50 of 57.7 mg/kg after administration of sarin, and it reduces reduces acute toxicity of sarin was evaluated[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: NMRI male mice
Dosage: 10 mg/kg
Administration: Intramuscular injection
Result: Was effective in reactivating sarin-inhibited acetylcholinesterase (AChE).
分子量

359.21

Formula

C14H16Cl2N4O3
CAS 号
性状

固体

颜色

Off-white to light yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

纯度 & 产品资料

纯度: 96.60%

COA (282 KB)

产品使用指南 (1538 KB)
参考文献

Obidoxime dichloride 相关分类

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Keywords:

Obidoxime dichloride114-90-9Cholinesterase (ChE)acutetoxicityacetylcholinesterasesarinInhibitorinhibitorinhibit

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