2. Apoptosis
  3. Apoptosis Caspase
  4. Patuletin

Patuletin  (Synonyms: 帕特列汀)

目录号: HY-N12503
产品使用指南

摩尔计算器

Patuletin 是一种黄酮醇，可以从 Tagetes patula 的花中分离出来。Patuletin 对癌细胞具有抗增殖活性。Patuletin 可引起显著的核碎裂，并且具有很强的诱导 caspase-3 激活的能力。

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Patuletin Chemical Structure

Patuletin Chemical Structure

CAS No. : 519-96-0

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Patuletin 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Patuletin is a flavonol, that can be isolated from the flowers of Tagetes patula. Patuletin shows anti-proliferative activity against cancer cells. Patuletin causes significant nuclear fragmentation and has a great capacity to induce caspase-3 activation[1][2].

IC50 & Target

Caspase 3

 

体外研究
(In Vitro)

Patuletin (0-100 μg/mL，24 h) 具有抗癌细胞增殖活性[2]。
Patuletin 可诱导 CaSki、MDA-MB-231 和 SK-Lu-1 细胞凋亡[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Patuletin 相关抗体:

Cell Proliferation Assay[2]

Cell Line: CaSki, MDA-MB-231 and SK-Lu-1
Concentration: 6, 12, 25, 50 and 100 μg/mL
Incubation Time: 24 h
Result: Showed a dose-dependent proliferation inhibition, with IC50 values of 37, 86, and 18 μg/mL for CaSki, MDA-MB-231 and SK-Lu-1 cells, respectively.
分子量

332.26

Formula

C16H12O8
CAS 号
中文名称

帕特列汀
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Patuletin 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Patuletin519-96-0帕特列汀ApoptosisCaspaseCaSkiMDA-MB-231SK-Lu-1Inhibitorinhibitorinhibit

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