2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. Procaterol hydrochloride

Procaterol hydrochloride  (Synonyms: 盐酸丙卡特罗)

目录号: HY-100704 纯度: ≥99.0%
COA 产品使用指南

摩尔计算器

Procaterol hydrochloride 是一种选择性的中效 β2 肾上腺素能受体激动剂，EC50 为 12.9 μM。Procaterol hydrochloride 可以抑制体内外炎症。

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Procaterol hydrochloride Chemical Structure

Procaterol hydrochloride Chemical Structure

CAS No. : 62929-91-3

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规格 价格 是否有货 数量
5 mg ￥1422
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Customer Review

Other Forms of Procaterol hydrochloride:

Procaterol hydrochloride 相关抗体

Top Publications Citing Use of Products

MCE 顾客使用本产品发表的 1 篇科研文献

查看 Adrenergic Receptor 亚型特异性产品:

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α adrenergic receptor β adrenergic receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Procaterol hydrochloride is a selective intermediate-acting β2 adrenoreceptor agonist with an EC50 of 12.9 μM[1]. Procaterol hydrochloride can inhibit inflammation both in vivo and in vitro[2].

体外研究
(In Vitro)

Procaterol treat inflammation through inhibiting oxidative stress in vitro[2].
Procaterol (25-200 nM) increases the viability of 16HBE cells[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Procaterol hydrochloride 相关抗体:

Cell Viability Assay[2]

Cell Line: The immortal human bronchial epithelial cell line (16HBE)
Concentration: 25-200 nM
Incubation Time: Pretreated for 20 hours
Result: Pretreatment elevated the cell viability rate in a dose-dependent manner. Pretreatment with Procaterol plus Dexamethasone could also significantly increase the cell viability rate, but the combined effect was not better than sole pretreatment with an identical dose of Procaterol.
体内研究
(In Vivo)

Procaterol significantly increases conditioned stimulus (CS)-evoked freezing levels[3]. Propranolol-mediated blockade of β-adrenergic receptors (β-ARs) significantly reduces behavioral expression of Pavlovian threat conditioning (PTC), whereas systemic activation of β2-ARs using Procaterol enhances it[3].
Procaterol hydrochloride is freshly dissolved in 0.9% sterile saline immediately prior to injections[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Adult male Sprague-Dawley rats, weighing 250-275 g (~60-70 days old)[3]
Dosage: 300 µg/kg
Administration: Intraperitoneal (IP) injection
Result: Systemic injection of the specific β2-AR agonist procaterol (300 µg/kg) enhanced CS-elicited freezing during the expression test, with no effect during a drug free test.
分子量

326.82

Formula

C16H23ClN2O3
CAS 号
性状

固体

颜色

White to off-white

中文名称

盐酸丙卡特罗
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
细胞实验： 

DMSO 中的溶解度 : 30 mg/mL (91.79 mM; 超声加热助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.0598 mL 15.2989 mL 30.5979 mL
5 mM 0.6120 mL 3.0598 mL 6.1196 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料

纯度: ≥99.0%

COA (291 KB)

产品使用指南 (1538 KB)
参考文献

Procaterol hydrochloride 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0598 mL 15.2989 mL 30.5979 mL 76.4947 mL
5 mM 0.6120 mL 3.0598 mL 6.1196 mL 15.2989 mL
10 mM 0.3060 mL 1.5299 mL 3.0598 mL 7.6495 mL
15 mM 0.2040 mL 1.0199 mL 2.0399 mL 5.0996 mL
20 mM 0.1530 mL 0.7649 mL 1.5299 mL 3.8247 mL
25 mM 0.1224 mL 0.6120 mL 1.2239 mL 3.0598 mL
30 mM 0.1020 mL 0.5100 mL 1.0199 mL 2.5498 mL
40 mM 0.0765 mL 0.3825 mL 0.7649 mL 1.9124 mL
50 mM 0.0612 mL 0.3060 mL 0.6120 mL 1.5299 mL
60 mM 0.0510 mL 0.2550 mL 0.5100 mL 1.2749 mL
80 mM 0.0382 mL 0.1912 mL 0.3825 mL 0.9562 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Procaterol62929-91-3盐酸丙卡特罗Adrenergic ReceptorBeta Receptorintermediate-actingβ2adrenoreceptorinflammationInhibitorinhibitorinhibit

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目录号：
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