1. 重组蛋白
  2. Cytokines and Growth Factors
  3. TNF Superfamily
  4. TNF Superfamily Ligands
  5. TNF-β

TNF-β  (肿瘤坏死因子-β)

TNF-β (tumor necrosis factor β) 又称淋巴毒素-α (LT-α),是肿瘤坏死因子超家族的成员,是一种由淋巴细胞产生的细胞因子。TNF-β 激活 NF-κB 信号通路,诱导癌细胞增殖、侵袭[1][2]。TNF-β 上调转移相关基因的表达,促进上皮-间质转化,刺激自身表达[3]。TNF-β 介导多种炎症、免疫刺激和抗病毒反应。

TNF-β (tumor necrosis factor β) also called lymphotoxin-α (LT-α), a member of the tumor necrosis factor superfamily, is a cytokine produced by lymphocytes. TNF-β activates the NF-κB signaling pathway, inducing cancer cell proliferation, invasion[1][2]. TNF-β up-regulates genes connected with metastasis, promotes epithelial-to-mesenchymal-transition, stimulates its own expression[3]. TNF-β mediates a large variety of inflammatory, immunostimulatory, and antiviral responses.

目录号 产品名 / 同用名 种属 表达系统
  • HY-P700228AF
    Animal-Free TNF beta Protein, Mouse (His)

    TNFSF1B; Lymphotoxin-alpha (LT-α); LTalpha; Ltx; TNF-be; TNFSF1; Tnf; Tnfb; Tnfsf; Tnfsf1b; Tnlg1e; hlb38; hlb382; lymph

    Mouse E. coli
    无动物源的 TNF β 蛋白作为同源三聚体细胞因子,结合 TNFRSF1A/TNFR1、TNFRSF1B/TNFBR 和 TNFRSF14/HVEM。Animal-Free TNF beta Protein, Mouse (His) 是重组的 无动物源 TNF β 蛋白,由 E. coli 表达,带有 N-His 标签。
  • HY-P700419
    TNF-beta/TNFSF1 Protein, Human (HEK293, His)

    LTA; lymphotoxin alpha (TNF superfamily, member 1); LT; TNFB; TNFSF1; lymphotoxin alpha; OTTHUMP00000165897; tumor necrosis factor beta; Tumor necrosis factor ligand superfamily member 1; TNF-beta; LT-alpha

    Human HEK293
    TNF-β 蛋白作为同源三聚体细胞因子,与 TNFRSF1A/TNFR1、TNFRSF1B/TNFBR 和 TNFRSF14/HVEM 结合。TNF-beta/TNFSF1 Protein, Human (HEK293, His) 是重组的 TNF-β/TNFSF1 蛋白,由 HEK293 表达,带有 N-6*His 标签。TNF-beta/TNFSF1 Protein, Human (HEK293, His) 全长 171 个氨基酸,分子量为 20.8 kDa。
  • HY-P700154AF
    Animal-Free TNF-beta/TNFSF1 Protein, Human (His)

    Lymphotoxin-Alpha; LT-Alpha; TNF-beta; Tumor Necrosis Factor Ligand Superfamily Member 1; LTA; TNFB; TNFSF1

    Human E. coli
    TNF-β 蛋白作为同源三聚体细胞因子,与 TNFRSF1A/TNFR1、TNFRSF1B/TNFBR 和 TNFRSF14/HVEM 结合。Animal-Free TNF-beta/TNFSF1 Protein, Human (His) 是重组的 无动物源 TNF-beta/TNFSF1 蛋白,由 E. coli 表达,带有 N-His 标签。Animal-Free TNF-beta/TNFSF1 Protein, Human (His) 全长 171 个氨基酸,分子量约为 ~18.65 kDa。
  • HY-P7304
    TNF-beta/TNFSF1 Protein, Human

    重组人肿瘤坏死因子 β

    rHuTNF-β; TNF-β; TNFSF1; Lymphotoxin-alpha

    Human E. coli
    TNF-β (tumor necrosis factor β) 又称淋巴毒素-α (LT-α),是肿瘤坏死因子超家族的成员,是一种由淋巴细胞产生的细胞因子。TNF-β 激活 NF-κB 信号通路,诱导癌细胞增殖、侵袭。TNF-β 上调转移相关基因的表达,促进上皮-间质转化,刺激自身表达。TNF-β 介导多种炎症、免疫刺激和抗病毒反应。TNF-beta/TNFSF1 Protein, Human 是一种由大肠杆菌表达的重组蛋白,由 171 个 (L35-L205) 氨基酸组成。
  • HY-P700612
    TNF-beta/TNFSF1 Protein, Human (HEK293, His-Avi)

    LTA; lymphotoxin alpha (TNF superfamily, member 1); LT; TNFB; TNFSF1; lymphotoxin alpha; OTTHUMP00000165897; tumor necrosis factor beta; Tumor necrosis factor ligand superfamily member 1; TNF-beta; LT-alpha

    Human HEK293
    TNF-β 蛋白作为同源三聚体细胞因子,与 TNFRSF1A/TNFR1、TNFRSF1B/TNFBR 和 TNFRSF14/HVEM 结合。TNF-beta/TNFSF1 Protein, Human (HEK293, His-Avi) 是重组的 TNF-β/TNFSF1 蛋白,由 HEK293 表达,带有 N-Avi, N-6*His 标签。TNF-beta/TNFSF1 Protein, Human (HEK293, His-Avi) 全长 171 个氨基酸,分子量为 22.7 kDa。
目录号 产品名 作用方式 纯度