Prussian blue insoluble  (Synonyms: Iron(III) ferrocyanide; Milori blue)

Prussian blue soluble is a good adsorbent to be used as antidotes for poisoning with cesium or thallium ions. Prussian blue soluble has anticancerous and antibacterial properties. Prussian blue soluble can be used as a contrast agent in photoacoustic and magnetic resonance imaging (MRI)^[1][2][3][4].

Prussian blue insoluble (Iron(III) ferrocyanide) (0.1-3.0μg/mL; 24 hours; HUVECs) has photo-thermal effect and inhibits cell viabilities^[1]. Prussian blue insoluble (Iron(III) ferrocyanide) (0.07 mM; 0-24 hours) act as a metabolic indicator, being reduced by bacterial metabolism, producing a visible color change from blue to colorless^[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Prussian blue insoluble (3 g/day; p.o.; for 8 days; rats)(Iron(III) ferrocyanide) can be used as a therapeutic agent in radiocesium and thallium poisoning^[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

859.23

C₁₈Fe₇N₁₈

14038-43-8

固体

Blue to dark blue

Room temperature in continental US; may vary elsewhere.

• [1]. Chen HJ, et, al. Facile synthesis of Prussian blue nanoparticles as pH-responsive drug carriers for combined photothermal-chemo treatment of cancer. RCS advances. 2016 Oct 9; 7:248-255.  [Content Brief]

  [2]. Ferrer-Vilanova A, et, al. Electrochromogenic Detection of Live Bacteria Using Soluble and Insoluble Prussian Blue. ACS Omega. 2021 Nov 11;6(46):30989-30997.  [Content Brief]

  [3]. Thompson DF, et, al. Soluble or insoluble prussian blue for radiocesium and thallium poisoning? Ann Pharmacother. 2004 Sep;38(9):1509-14.  [Content Brief]

  [4]. Busquets MA, et, al. Prussian blue nanoparticles: synthesis, surface modification, and biomedical applications. Drug Discov Today. 2020 Aug;25(8):1431-1443.  [Content Brief]