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  5. FDA抗癌化合物库
FDA抗癌化合物库 - FDA-Approved Anticancer Drug Library

Cat. No.: HY-L122

癌症是全球第二大死亡原因,严重威胁人类健康。目前已经开发出多种癌症治疗方法,但新的抗癌药物仍然亟待开发。由于获得批准上市的药物具有良好的生物活性、安全性和生物利用度,可以大大加快药物的开发速度。

MCE提供了1,436种批准上市且具有抗癌活性的药物,可用于发现新的抗癌药物或作为抗癌研究的阳性化合物。

我们将在明确您的产品用途后,向符合资质的客户通过定制合成服务的方式提供 MCE FDA抗癌化合物库,我们为该库中的所有产品提供溶液包装或粉末包装。溶液包装中,1,387 个产品以 10 mM 浓度提供,34 个产品以 2 mM 浓度提供,15 个产品以 3 mg/mL 浓度提供。

溶液包装中,我们对于溶液状态稳定且溶解度不低于 10 mM 的产品,提供 10 mM 溶液;对于溶液状态稳定且溶解度介于 2~10 mM 的产品,我们提供 2 mM 溶液;对于溶液状态稳定、分子量不确定且溶解度不低于 3 mg/mL产品,我们提供 3 mg/mL 溶液。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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Compound Screening Libraries

Top Publications Citing Use of MCE Products

MCE 顾客使用化合物库产品发表的文献

  • 生物活性
  • 产品详情
  • 化合物库组成

活性描述 & 特点

Biological Activity

•   A unique collection of 1,436 approved drugs with anti-cancer activity for high throughput screening (HTS) and high content screening (HCS).

•   A useful tool for anti-cancer research and drug repurposing.

•   All compounds have been approved by the FDA, EMA and other countries.

•   Structurally diverse, bioactive, and cell permeable.

•   More detailed compound information with structure, IC50, and brief introduction.

•   NMR and HPLC validated ensure high purity.

•   All compounds are in stock and continuously updated.

产品详情

Product Details

Formulation:

A collection of 1,436 approved anti-cancer drugs supplied as pre-dissolved Solutions or Solid
Solution: 1,387 compounds supplied in 10 mM solution, 34 compounds supplied in 2 mM solution, 15 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice

化合物库组成

Composition

COX (50)

HIV (47)

VEGFR (32)

EGFR (29)

PDGFR (25)

c-Kit (21)

FGFR (21)

mAChR (18)

Akt (14)

CDK (14)

HSV (14)

PARP (13)

PPAR (13)

HDAC (12)

Src (12)

STAT (12)

FLT3 (11)

JAK (11)

PI3K (11)

MEK (10)

nAChR (10)

Raf (10)

PKC (9)

Btk (8)

ERK (8)

HBV (8)

AMPK (7)

MMP (7)

RET (7)

ROCK (7)

CMV (6)

HCV (6)

相关服务推荐
定制您专属的化合物库
  •  特定化合物
  •  化合物数量
  •  产品排布图
  •  浓度
  •  形式(固体或溶液)
  •  YES
联系专家定制
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack

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    产品名称:
    FDA-Approved Anticancer Drug Library
    目录号:
    HY-L122
    需求量: