1. 重组蛋白
  2. Immune Checkpoint Proteins CD Antigens
  3. Inhibitory Checkpoint Molecules T Cell CD Proteins Macrophage CD Proteins
  4. PD-1
  5. PD-1 蛋白, Canine (HEK293, His)

PD-1 蛋白, Canine (HEK293, His)

目录号: HY-P73342
COA 产品使用指南

Angiopoietin-1 蛋白是一种分泌糖蛋白,是血管酪氨酸激酶信号通路的关键配体。ANGPT1 通过激活 PTK2/FAK 及下游激酶 MAPK1/ERK2MAPK3/ERK1 信号通路刺激血管新生。ANGPT1 影响成骨骼肌细胞的增殖、迁移和分化。PD-1 蛋白, Canine (HEK293, His) 是重组的 PD-1 蛋白,由 HEK293 表达,带有 C-His 标签。PD-1 蛋白, Canine (HEK293, His) 全长 145 个氨基酸,分子量约为 ~34.88 and 65.02 kDa。

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规格 价格 是否有货 数量
10 μg ¥1450 In-stock
20 μg ¥2350 In-stock
50 μg ¥4400 In-stock
100 μg   询价  

* Please select Quantity before adding items.

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

The Angiopoietin-1 Protein is a secreted glycoprotein that is a key ligand in the vascular tyrosine kinase signaling pathway. ANGPT1 stimulates angiogenesis by activating PTK2/FAK and downstream kinase MAPK1/ERK2 and MAPK3/ERK1 signaling pathways. ANGPT1 affects the proliferation, migration and differentiation of skeletal muscle cells. PD-1 Protein, Canine (HEK293, His) is the recombinant canine-derived PD-1 protein, expressed by HEK293 , with C-His labeled tag. The total length of PD-1 Protein, Canine (HEK293, His) is 145 a.a., with molecular weight of ~34.88 and 65.02 kDa.

研究背景

血管生成素-1 (ANGPT1) 编码血管生成素家族中的一种分泌糖蛋白,是血管酪氨酸激酶信号通路的关键配体。ANGPT1 通过激活 PTK2/FAK 及下游激酶 MAPK1/ERK2MAPK3/ERK1 信号通路刺激血管新生。Angiopoietin-1 Protein 调节血管的形成和稳定,在血管发育中有重要作用。ANGPT1 影响成骨骼肌细胞的增殖、迁移和分化。

生物活性

Measured by its ability to bind biotinylated human B7-H1-Fc in functional ELISA.

种属

Canine

表达系统

HEK293

标签

C-His

蛋白编号

XP_543338.3 (L25-L169)

基因 ID
蛋白结构
N-term
PD-1 (L25-L169)
Accession # XP_543338.3
His
C-term
同用名
CD279; hPD-1; PDCD1; Programmed cell death 1; SLEB2
分子量

Approximately 34.88 and 65.02 kDa

纯度

Greater than 95% as determined by SEC-HPLC.

性状

溶液

组分

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

N/A.

保存条件 & 期限

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

运输条件

Shipping with dry ice.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
PD-1 Protein, Canine (HEK293, His)
目录号:
HY-P73342
需求量: