1. Metabolic Enzyme/Protease Neuronal Signaling Anti-infection
  2. Phospholipase Cholinesterase (ChE) Bacterial
  3. SMase-IN-1

SMase-IN-1 (Compound 4) 是一种细菌鞘磷脂酶 (SMase) 抑制剂 (对蜡样芽孢杆菌 SMase 的IC50 值为 6.43 µM)。SMase-IN-1 还能抑制 eqBuChE (50 µM 浓度时抑制率为 59.50%)。SMase-IN-1 以生物-金属相互作用与 Cu2+ 形成复合物。SMase-IN-1 可抑制蜡样芽孢杆菌诱导的绵羊红细胞溶血。

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SMase-IN-1 Chemical Structure

SMase-IN-1 Chemical Structure

CAS No. : 33017-85-5

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  • 生物活性

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  • 参考文献

生物活性

SMase-IN-1 (Compound 4) is a bacterial sphingomyelinase enzyme (SMase) inhibitor (IC50 value for B. cereus SMase is 6.43 µM). SMase-IN-1 also inhibits eqBuChE (59.50% inhibition rate at 50 µM concentration). SMase-IN-1 forms a complex with Cu2+ in biometal interactions. SMase-IN-1 reduces B. cereus-induced hemolysis on sheep erythrocytes[1].

分子量

212.66

Formula

C8H5ClN2OS

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
SMase-IN-1
目录号:
HY-170650
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