2. Apoptosis Immunology/Inflammation NF-κB PI3K/Akt/mTOR Metabolic Enzyme/Protease
  3. TNF Receptor Interleukin Related Reactive Oxygen Species PI3K
  4. Taxamairin B

Taxamairin B 是一种有效的抗炎剂。Taxamairin B 降低 LPS 诱导的 RAW264.7 细胞中促炎因子 (TNF-α, IL-1β 和 IL-6) 的表达和 NO，ROS 的产生。Taxamairin B 对 LPS 诱导的急性肺损伤小鼠有明显的保护作用。

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Taxamairin B Chemical Structure

Taxamairin B Chemical Structure

CAS No. : 110300-77-1

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Taxamairin B 相关抗体

Top Publications Citing Use of Products

查看 TNF Receptor 亚型特异性产品:

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TNFRSF1A/CD120a TNFRSF5/CD40 TNFRSF6/Fas/CD95 TNFRSF8/CD30 TNFRSF9/4-1BB/CD137 TNFRSF16/NGF Receptor/CD271 TNFRSF18/GITR/CD357

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PI3Kα PI3Kβ PI3Kγ PI3Kδ PI3KC2α PI3KC2β PI3KC2γ Vps34 PI3K PI3KC3 p120γ

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Taxamairin B is a potent anti-inflammatory agent. Taxamairin B decreases proinflammatory cytokines (TNF-α, IL-1β and IL-6) expression and the production of NO and ROS in LPS-induced RAW264.7 cells. Taxamairin B exhibits significant protective effects in LPS-induced acute lung injury in mice[1][2].

分子量

352.42

Formula

C22H24O4
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Taxamairin B 相关分类

  • 摩尔计算器

  • 稀释计算器

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质量   浓度   体积   分子量 *
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Taxamairin B110300-77-1TNF ReceptorInterleukin RelatedReactive Oxygen SpeciesPI3KTumor Necrosis Factor ReceptorTNFRILPhosphoinositide 3-kinaseTNF-αIL-1βIL-6NOROSRAW264.7PI3K-AKT pathwayAnti-inflammatory agentAcute lung injuryInhibitorinhibitorinhibit

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