2. Anti-infection
  3. HBV
  4. TLR8 agonist 4

TLR8 agonist 4 对野生型和耐药（拉米夫定和恩替卡韦）HBV菌株均表现出有效的抑制作用。其IC50值分别为 0.15 和 0.10 μM。

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TLR8 agonist 4 Chemical Structure

TLR8 agonist 4 Chemical Structure

CAS No. : 2761697-69-0

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TLR8 agonist 4 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

TLR8 agonist 4 showed effective inhibition on wild-type and drug-resistant (lamivudine and entecavir) HBV strains. The IC50 values are 0.15 and 0.10 respectively μM.

IC50 & Target

HBV

0.10 μM (IC50)

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HepG2 2.2.15 CC50
> 10 μM
Compound: 5l
Cytotoxicity against human HepG2 2.2.15 cells infected with Hepatitis B virus assessed as reduction in cell growth by CCK8 assay
Cytotoxicity against human HepG2 2.2.15 cells infected with Hepatitis B virus assessed as reduction in cell growth by CCK8 assay
[PMID: 35123297]
分子量

545.61

Formula

C28H27N5O5S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

TLR8 agonist 4 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TLR8 agonist 42761697-69-0HBVHepatitis B virusInhibitorinhibitorinhibit

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TLR8 agonist 4
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