1. Membrane Transporter/Ion Channel
  2. Calmodulin
  3. W-5 hydrochloride

W-5 hydrochloride  (Synonyms: N-(6-氨基己基)-1-萘磺酰胺盐酸盐)

目录号: HY-100911
产品使用指南

W-5 hydrochloride 是一种钙调蛋白 (calmodulin) 拮抗剂。W-5 hydrochloride 可抑制磷酸二酯酶 (phosphodiesterase) 活性,其 IC50 值为 240 µM。W-5 hydrochloride 可用作 W-7 (HY-100912) 的阴性对照。

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W-5 hydrochloride Chemical Structure

W-5 hydrochloride Chemical Structure

CAS No. : 61714-25-8

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

W-5 hydrochloride is a calmodulin antagonist. W-5 hydrochloride inhibits phosphodiesterase activation with an IC50 value of 240 µM. W-5 hydrochloride can be used as a negative control for W-7 (HY-100912)[1][2].

IC50 & Target

IC50: 240 µM (phosphodiesterase)[1]

体外研究
(In Vitro)

W-5 hydrochloride (40 µM; 24 h; incubation with 10 μg/mL of apolipoprotein A-I (apoA-I)) 可增加胆固醇和胆碱磷脂的流出[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

342.88

Formula

C16H23ClN2O2S

CAS 号
中文名称

N-(6-氨基己基)-1-萘磺酰胺盐酸盐

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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W-5 hydrochloride
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HY-100911
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