2. Neuronal Signaling
  3. Cholinesterase (ChE)
  4. Z32439948

Z32439948 是丁酰胆碱酯酶 (BChE) 抑制剂 (IC50: 1.4 μM, hBChE)，是间氨磺酰苯甲酰胺的衍生物。Z32439948 还在 SH-SY5Y 细胞中表现出抗谷氨酸的神经保护作用。

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Z32439948 Chemical Structure

Z32439948 Chemical Structure

CAS No. : 920845-86-9

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Z32439948 相关抗体

Top Publications Citing Use of Products

查看 Cholinesterase (ChE) 亚型特异性产品:

查看所有亚型
AChE BChE

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Z32439948 is a butyrylcholinesterase (BChE) inhibitor (IC50: 1.4 μM, hBChE) and is a derivative of m-sulfamoylbenzamide. Z32439948 also exhibited neuroprotective effects against glutamate in SH-SY5Y cells[1].

IC50 & Target

BChE

1.4 μM (IC50, [1])

体外研究
(In Vitro)

Z32439948 (1-5 μM; 48 h) 对谷氨酸 (31 mM) 诱导的 SH-SY5Y 细胞死亡具有神经保护作用[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Z32439948 相关抗体:

Cell Viability Assay[1]

Cell Line: SH-SY5Y, BV2 cells
Concentration: 1 μM, 2 μM, 5 μM
Incubation Time: 48 h; with or without 31 mM Glutamate
Result: Protected cell from Glutamate induced damage.
分子量

478.56

Formula

C25H26N4O4S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Z32439948 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Z32439948920845-86-9Z 32439948Z-32439948Cholinesterase (ChE)MetasulfamoylbenzamideneuroprotectionglutamateInhibitorinhibitorinhibit

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产品名称：
Z32439948
目录号：
HY-162340
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