2. Membrane Transporter/Ion Channel
  3. Sodium Channel
  4. δ-Buthitoxin-Hj2a

δ-Buthitoxin-Hj2a 是一种蝎毒肽，是一种有效的 NaV1.1 激动剂，EC50 为 32 nM。δ-Buthitoxin-Hj2a 可用于 Dravet 综合征 (DS) 研究。

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Custom Peptide Synthesis

δ-Buthitoxin-Hj2a Chemical Structure

δ-Buthitoxin-Hj2a Chemical Structure

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δ-Buthitoxin-Hj2a 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

δ-Buthitoxin-Hj2a, a scorpion-venom peptide, is a potent NaV1.1 agonist with an EC50 of 32 nM. δ-Buthitoxin-Hj2a can be used for the Dravet syndrome (DS) research[1].

IC50 & Target[1]

Nav1.1

32 nM (EC50)

分子量

7117.96

Formula

C304H458N90O93S8
Sequence

Gly-Arg-Asp-Ala-Tyr-Ile-Ala-Asp-Asp-Lys-Asn-Cys-Val-Tyr-Thr-Cys-Ala-Lys-Asn-Ser-Tyr-Cys-Asn-Asn-Glu-Cys-Thr-Lys-Asn-Gly-Ala-Glu-Ser-Gly-Tyr-Cys-Gln-Trp-Leu-Gly-Lys-Tyr-Gly-Asn-Gly-Cys-Trp-Cys-Lys-Asn-Leu-Pro-Asp-Lys-Val-Pro-Ile-Arg-Ile-Pro-Gly-Pro-Cys-Arg-NH2 (Disulfide bridge:(Disulfide bridge:Cys12-Cys63;Cys16-Cys36;Cys22-Cys46;Cys26-Cys48)
Sequence Shortening

GRDAYIADDKNCVYTCAKNSYCNNECTKNGAESGYCQWLGKYGNGCWCKNLPDKVPIRIPGPCR-NH2 (Disulfide bridge:(Disulfide bridge:Cys12-Cys63;Cys16-Cys36;Cys22-Cys46;Cys26-Cys48)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

δ-Buthitoxin-Hj2a 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

δ-Buthitoxin-Hj2aSodium ChannelNa channelsNa+ channelsNaV1.1scorpion-venom peptideDravet syndromeInhibitorinhibitorinhibit

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目录号：
HY-P5783
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