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  4. 2-Iodoestradiol

2-Iodoestradiol是一种有效的人类性激素结合球蛋白（SHBG）配体，具有对SHBG的显著高亲和力。2-Iodoestradiol在与人类SHBG的结合中，显示出与二氢睾酮相同的结合位点竞争能力。2-Iodoestradiol在生理pH和37摄氏度下的结合亲和常数为2.4 x 10(9) M-1，超过了对SHBG的结合。2-Iodoestradiol被证实与血清白蛋白结合，但亲和力较低。2-Iodoestradiol的放射性同位素125I-衍生物被用于研究人类SHBG的结合特性，显示其在生物学研究中的潜在应用。

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2-Iodoestradiol Chemical Structure

2-Iodoestradiol Chemical Structure

CAS No. : 24381-12-2

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2-Iodoestradiol 相关抗体

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生物活性

2-Iodoestradiol is a potent human sex hormone binding globulin (SHBG) ligand with a remarkably high affinity for SHBG. 2-Iodoestradiol exhibits competition for the same binding site as dihydrotestosterone in binding to human SHBG. The binding affinity constant of 2-Iodoestradiol at physiological pH and 37 degrees Celsius is 2.4 x 10(9) M-1, exceeding that for SHBG. 2-Iodoestradiol has been shown to bind to serum albumin, but with lower affinity. The radioisotope 125I-derivative of 2-Iodoestradiol has been used to study the binding properties of human SHBG, demonstrating its potential application in biological research[1].

分子量

398.28

Formula

C18H23IO2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
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2-Iodoestradiol 相关分类

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Keywords:

2-Iodoestradiol24381-12-2OthersInhibitorinhibitorinhibit

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