1. Cell Cycle/DNA Damage
  2. Nucleoside Antimetabolite/Analog
  3. 2′-O-2-Propyn-1-ylguanosine

2′-O-2-Propyn-1-ylguanosine 

目录号: HY-152684
产品使用指南

2′-O-2-Propyn-1-ylguanosine 是一种鸟嘌呤核苷类似物。鸟嘌呤核苷类似物具有免疫刺激活性。在一些动物模型中,它们还诱导 I 型干扰素,产生抗病毒作用。研究表明,鸟苷类似物的功能活性依赖于活化 Toll 样受体 7 (TLR7)。2′-O-2-Propyn-1-ylguanosine 是一种点击化学试剂。它含有 Alkyne 基团,可以和含有 Azide 基团的分子发生铜催化的叠氮-炔环加成反应 (CuAAc)。

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2′-O-2-Propyn-1-ylguanosine Chemical Structure

2′-O-2-Propyn-1-ylguanosine Chemical Structure

CAS No. : 206552-86-5

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规格 价格 是否有货 数量
1 mg ¥1020
1 - 2 周
5 mg ¥2580
1 - 2 周
10 mg ¥3480
1 - 2 周
50 mg   询价  
100 mg   询价  

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

2′-O-2-Propyn-1-ylguanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1]. 2′-O-2-Propyn-1-ylguanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

分子量

321.29

Formula

C13H15N5O5

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
2′-O-2-Propyn-1-ylguanosine
目录号:
HY-152684
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