2. Cell Cycle/DNA Damage Metabolic Enzyme/Protease
  3. Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Endogenous Metabolite
  4. 3'-Deoxyuridine-5'-triphosphate

3'-Deoxyuridine-5'-triphosphate  (Synonyms: 3'-dUTP)

目录号: HY-135780
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摩尔计算器

3'-Deoxyuridine-5'-triphosphate (3'-dUTP) 是一种核苷酸类似物，可抑制 DNA 依赖性 RNA 聚合酶 I 和 II (RNA polymerases I 和 II)，强烈并竞争性地抑制 UTP 掺入到 RNA 中，Ki 值为 2.0 μM。

在相同的摩尔浓度下，化合物盐形式与游离形式有相同的生物活性，但盐形式 3'-Deoxyuridine-5'-triphosphate trisodium 通常具有更好的水溶性和稳定性。

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3'-Deoxyuridine-5'-triphosphate Chemical Structure

3'-Deoxyuridine-5'-triphosphate Chemical Structure

CAS No. : 69199-40-2

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3'-Deoxyuridine-5'-triphosphate 的其他形式现货产品:

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Other Forms of 3'-Deoxyuridine-5'-triphosphate:

3'-Deoxyuridine-5'-triphosphate 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

3'-Deoxyuridine-5'-triphosphate (3'-dUTP) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II. 3'-Deoxyuridine-5'-triphosphate strongly and competitively inhibits the incorporations of UTP into RNA with a Ki value of 2.0 μM[1].

体外研究
(In Vitro)

3'-Deoxyuridine-5'-triphosphate (3'-dUTP) is synthesized starting from cordycepin in good yield. 3'-Deoxyuridine-5'-triphosphate strongly and competitively inhibits the incorporations of UTP into RNA by the RNA polymerases. 3'-Deoxyuridine-5'-triphosphate will be useful in studies at the molecular level on the relationship of template and substrate in RNA synthesis with chromatin, isolated nuclei or permeable cells, because it does not have any effect on poly (rA) synthesis[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

3'-Deoxyuridine-5'-triphosphate 相关抗体:
分子量

468.14

Formula

C9H15N2O14P3
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

3'-Deoxyuridine-5'-triphosphate 相关分类

  • 摩尔计算器

  • 稀释计算器

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Keywords:

3'-Deoxyuridine-5'-triphosphate69199-40-23'-dUTPNucleoside Antimetabolite/AnalogDNA/RNA SynthesisEndogenous MetaboliteDNA-dependentRNApolymerases Ipolymerases IIUTPInhibitorinhibitorinhibit

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