2. GPCR/G Protein Neuronal Signaling Immunology/Inflammation Membrane Transporter/Ion Channel NF-κB Metabolic Enzyme/Protease
  3. Histamine Receptor Calcium Channel Cholinesterase (ChE) Reactive Oxygen Species Amyloid-β
  4. AChE/BChE-IN-21

AChE/BChE-IN-21 是一种组胺 H3 受体拮抗剂、钙通道阻滞剂和乙酰胆碱酯酶抑制剂。AChE/BChE-IN-21 对 H2O2 和 Aβ1-40 具有神经保护活性，并可以恢复 AD 小鼠的认知功能。

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AChE/BChE-IN-21 Chemical Structure

AChE/BChE-IN-21 Chemical Structure

CAS No. : 2756368-79-1

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AChE/BChE-IN-21 相关抗体

Top Publications Citing Use of Products

查看 Histamine Receptor 亚型特异性产品:

查看所有亚型
H1 Receptor H2 Receptor H3 Receptor H4 Receptor Histamine Receptor

查看 Calcium Channel 亚型特异性产品:

查看所有亚型
N-type calcium channel L-type calcium channel P/Q-type calcium channel T-type calcium channel Calcium Channel

查看 Cholinesterase (ChE) 亚型特异性产品:

查看所有亚型
AChE BChE

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AChE/BChE-IN-21 is a histamine H3 receptor antagonist, calcium channel blocker, and acetylcholinesterase inhibitor. AChE/BChE-IN-21 exhibits neuroprotective activity against H2O2 and Aβ1-40, and can restore cognitive function in AD mice[1].
分子量

630.86

Formula

C38H54N4O4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

AChE/BChE-IN-21 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AChE/BChE-IN-212756368-79-1Histamine ReceptorCalcium ChannelCholinesterase (ChE)Reactive Oxygen SpeciesAmyloid-βCa2+ channelsCa channelsβ-amyloid peptideAβAbetahistamine H3 receptorcalcium channelacetylcholinesteraseneuroprotectiveInhibitorinhibitorinhibit

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