1. Antibody-drug Conjugate/ADC Related Cytoskeleton Cell Cycle/DNA Damage
  2. Drug-Linker Conjugates for ADC Microtubule/Tubulin
  3. Aminobenzenesulfonic auristatin E-d8

Aminobenzenesulfonic auristatin E-d8 

目录号: HY-145989S 纯度: 98.02%
COA 产品使用指南

Aminobenzenesulfonic auristatin E-d8 是 Aminobenzenesulfonic auristatin E 氘代物。Aminobenzenesulfonic auristatin E 是抗体偶联药物的一部分。Aminobenzenesulfonic auristatin E 由细胞毒性微管蛋白修饰剂 Auristatin E 和 ADC linker Aminobenzenesulfonic 连接而成,具有抗肿瘤活性。

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Aminobenzenesulfonic auristatin E-d<sub>8</sub> Chemical Structure

Aminobenzenesulfonic auristatin E-d8 Chemical Structure

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规格 价格 是否有货 数量
1 mg ¥9600
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Other Forms of Aminobenzenesulfonic auristatin E-d8:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Aminobenzenesulfonic auristatin E-d8 is the deuterium labeled Aminobenzenesulfonic auristatin E. Aminobenzenesulfonic auristatin E is a drug-linker conjugate for ADC. Aminobenzenesulfonic auristatin E has potent antitumor activity by using Auristatin E (a cytotoxic tubulin modifier), linked via the ADC linker Aminobenzenesulfonic[1][2].

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

761.05

Formula

C37H56D8N6O8S

非标记 CAS

1800462-99-0

性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Aminobenzenesulfonic auristatin E-d8
目录号:
HY-145989S
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