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  5. Anhydro-6-epiophiobolin A

Anhydro-6-epiophiobolin A 是 蛇毒碱 A 的类似物，是一种有效的光合作用 (photosynthesis) 抑制剂 (对小球藻和菠菜光合作用的 I50 分别为 6.1 和 1 mM)。

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Anhydro-6-epiophiobolin A Chemical Structure

Anhydro-6-epiophiobolin A Chemical Structure

CAS No. : 90411-20-4

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Other Forms of Anhydro-6-epiophiobolin A:

Anhydro-6-epiophiobolin A 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anhydro-6-epiophiobolin A, an analog of Ophiobolin A, is a potent inhibitor of photosynthesis (I50s of 6.1 and 1 mM for photosynthesis in Chlorella and Spinach, respectively)[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
> 40 μM
Compound: 10
Cytotoxicity against human A549 cells by MTT assay
Cytotoxicity against human A549 cells by MTT assay
[PMID: 31573805]
A549 GI50
9 μM
Compound: 9
Antiproliferative activity against human A549 cells by MTT assay
Antiproliferative activity against human A549 cells by MTT assay
[PMID: 26341136]
HepG2 IC50
> 40 μM
Compound: 10
Cytotoxicity against human HepG2 cells by MTT assay
Cytotoxicity against human HepG2 cells by MTT assay
[PMID: 31573805]
HepG2 IC50
47.1 μM
Compound: 3
Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
[PMID: 23668986]
Hs 683 GI50
8 μM
Compound: 9
Antiproliferative activity against human Hs683 cells by MTT assay
Antiproliferative activity against human Hs683 cells by MTT assay
[PMID: 26341136]
K562 IC50
35.6 μM
Compound: 3
Cytotoxicity against human K562 cells after 48 hrs by MTT assay
Cytotoxicity against human K562 cells after 48 hrs by MTT assay
[PMID: 23668986]
MCF7 GI50
10 μM
Compound: 9
Antiproliferative activity against human MCF7 cells by MTT assay
Antiproliferative activity against human MCF7 cells by MTT assay
[PMID: 26341136]
MDA-MB-231 IC50
> 40 μM
Compound: 10
Cytotoxicity against human MDA-MB-231 cells by MTT assay
Cytotoxicity against human MDA-MB-231 cells by MTT assay
[PMID: 31573805]
RAW264.7 IC50
5.1 μM
Compound: 10
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production pretreated for 2 hrs followed by LPS challenge and measured after 12 hrs by Griess assay
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production pretreated for 2 hrs followed by LPS challenge and measured after 12 hrs by Griess assay
[PMID: 31573805]
SK-MEL-28 GI50
8 μM
Compound: 9
Antiproliferative activity against human SK-MEL-28 cells by MTT assay
Antiproliferative activity against human SK-MEL-28 cells by MTT assay
[PMID: 26341136]
SW1990 IC50
> 40 μM
Compound: 10
Cytotoxicity against human SW1990 cells by MTT assay
Cytotoxicity against human SW1990 cells by MTT assay
[PMID: 31573805]
U-373MG ATCC GI50
18 μM
Compound: 9
Antiproliferative activity against human U373 cells by MTT assay
Antiproliferative activity against human U373 cells by MTT assay
[PMID: 26341136]
分子量

382.54

Formula

C25H34O3
CAS 号
结构分类
初始来源

Helminthosporium
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Anhydro-6-epiophiobolin A 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anhydro-6-epiophiobolin A90411-20-4OthersOphiobolin AanalogphotosynthesisInhibitorinhibitorinhibit

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