Pyruvate Dehydrogenase E1 alpha 抗体 (YA681)

Pyruvate Dehydrogenase E1 alpha Antibody (YA681) is a non-conjugated and Mouse origined monoclonal antibody about 43 kDa, targeting to Pyruvate Dehydrogenase E1 alpha (3H2). It can be used for WB,ICC/IF assays with tag free, in the background of Human, Mouse.

Pyruvate Dehydrogenase E1 alpha (3H2)：丙酮酸脱氢酶 (PDH) 复合物是一种核编码的线粒体多酶复合物，可催化丙酮酸向乙酰辅酶 A 和 CO(2) 的整体转化，并提供糖酵解和三羧酸 (TCA) 循环之间的主要联系。PDH 复合物由三种酶成分的多个拷贝组成：丙酮酸脱氢酶 (E1)、二氢硫辛酰胺乙酰转移酶 (E2) 和硫辛酰胺脱氢酶 (E3)。E1 酶是两个 α 和两个 β 亚基的异四聚体。该基因编码含有 E1 活性位点的 E1 alpha 1 亚基，在 PDH 复合体的功能中起关键作用。该基因的突变与丙酮酸脱氢酶 E1-α 缺乏症和 X 连锁 Leigh 综合征有关。已发现该基因编码不同亚型的可变剪接转录本变体。[由 RefSeq 提供，2010 年 3 月]

Free

5160

Predicted band size: 43 kDa

affinity purified

Non-conjugated

Unmodified

Signal Transduction

Primary Antibody; Mouse Monoclonal Antibody

Monoclonal

Mouse

Human, Mouse

P08559

WB: 1:500-1:1,000 ;IF: 1:50-1:200

WB, ICC/IF

液体

Supplied in 1*PBS (pH 7.3), 50% glycerol and 0.5% BSA. Preservative: 0.02% sodium azide.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG1

Endogenous

Synthetic peptide corresponding to Human Pyruvate Dehydrogenase E1 alpha.The exact sequence is proprietary to MCE.