2. Apoptosis
  3. Apoptosis
  4. Anticancer agent 237

Anticancer agent 237 (compound 13) 是一种有效的抗癌剂。Anticancer agent 237 具有细胞毒性。Anticancer agent 237 诱导细胞凋亡 (apoptosis) 和细胞周期停滞在 S 和 G2/M 期。

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Anticancer agent 237 Chemical Structure

Anticancer agent 237 Chemical Structure

CAS No. : 17822-61-6

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Anticancer agent 237 相关抗体

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生物活性

Anticancer agent 237 (compound 13) is a potent anticancer agent. Anticancer agent 237 shows cytotoxicity. Anticancer agent 237 induces apoptosis and cell cycle arrest at the S and G2/M phases[1].

体外研究
(In Vitro)

Anticancer agent 237 (compound 13) (48 h) 诱导 HCT-116、MCF-7 细胞凋亡和细胞周期停滞于 S 和 G2/M 期[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Anticancer agent 237 相关抗体:

Cell Cytotoxicity Assay[1]

Cell Line: HCT-116, MCF-7 cells
Concentration: 0-100 µM
Incubation Time: 48 h
Result: Showed cytotoxicity with IC50s of 43.5, 62.4 µM for HCT-116, MCF-7 cells, respectively.

Apoptosis Analysis[1]

Cell Line: HCT-116, MCF-7 cells
Concentration: 43.5 for HCT-116 cells, 62.4 for MCF-7 cells µM
Incubation Time: 48 h
Result: Induced apoptosis with 2.24% of the population being in early apoptosis, 0.58% in late apoptosis, and 6.6% in the necrotic population in MCF-7 cells, led to 45.07% of the population being in early apoptosis, 0.42% in late apoptosis, and 0.02% necrotic population in HCT-116 cells.

Cell Cycle Analysis[1]

Cell Line: HCT-116, MCF-7 cells
Concentration: 0-100 µM
Incubation Time: 48 h
Result: Induced cell cycle arrest at the S and G2/M phases.
分子量

348.46

Formula

C18H24N2O3S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
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Anticancer agent 237 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

Anticancer agent 23717822-61-6Anticancer agent237Anticancer agent-237ApoptosisanticancerG2/M phasesS phasesHCT-116MCF-7 cellscytotoxicityInhibitorinhibitorinhibit

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