2. Anti-infection
  3. SARS-CoV Influenza Virus RSV HSV
  4. Antiviral agent 58

Antiviral agent 58 (Compound J1) 是一种具有口服活性的抗病毒剂，对包膜病毒具有广谱抗病毒活性，包括甲型流感病毒 (IAV)、呼吸道合胞病毒 (RSV)、严重急性呼吸综合征冠状病毒 2 (SARS-CoV-2)、人冠状病毒OC43 (HCoV-OC43)、单纯疱疹病毒 1 型 (HSV-1) 和 HSV-2。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

我们将采用定制合成服务的方式为您快速提供所需产品和技术服务

Antiviral agent 58 Chemical Structure

Antiviral agent 58 Chemical Structure

CAS No. : 939655-35-3

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

Antiviral agent 58 相关抗体

Top Publications Citing Use of Products

查看 HSV 亚型特异性产品:

查看所有亚型
HSV-1 HSV-2 HSV

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antiviral agent 58 (Compound J1) is an orally active antiviral agent with broad-spectrum antiviral activity against enveloped viruses, including influenza A virus (IAV), respiratory syncytial virus (RSV), severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), human coronavirus OC43 (HCoV-OC43), herpes simplex virus type 1 (HSV-1), and HSV-2[1].

体外研究
(In Vitro)

Antiviral agent 58 (Compound J1) (6.25-200 μM; 48 h) 在 A549、MDCK、Vero-E6、HRT18 细胞中在 200μM 浓度下对细胞具有较低的细胞毒作用[1]。
Antiviral agent 58 能抑制 H1N1、H7N9、H5N1 和 H3N2 等 IAV 毒株以及奥司他韦耐药 (HY-13317) 毒株的感染, IC50 值在 7.81-15.65 μM 之间[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antiviral agent 58 相关抗体:
体内研究
(In Vivo)

Antiviral agent 58 (Compound J1) (15-60 mg/kg; 口服; 一天一次，连续 5 天) 在 BALB/c 小鼠中显著减轻 IAV 诱导的肺损伤[1]。 model: IAV lung injury BALB/c mouse model[1]. dose: 15 mg/kg; 30 mg/kg; 60 mg/kg administration: Oral, once daily for 5 days result: Increased the survival rate of virus-infected mice, and decreased viral titer, lung index and lung inflammation damage.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: IAV lung injury BALB/c mouse model[1].
Dosage: 15 mg/kg; 30 mg/kg; 60 mg/kg
Administration: Oral, once daily for 5 days
Result: Increased the survival rate of virus-infected mice, and decreased viral titer, lung index and lung inflammation damage.
分子量

399.87

Formula

C24H18ClN3O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antiviral agent 58 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antiviral agent 58939655-35-3Antiviral agent58Antiviral agent-58SARS-CoVInfluenza VirusRSVHSVSARS coronavirusRespiratory syncytial virusHerpes simplex virusInfluenza A virus (IAV)Vero-E6 cellsHRT18 cellsHEp-2 cellsVero cellsMDCK cellsInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Antiviral agent 58
目录号：
HY-162701
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z