2. Anti-infection
  3. Bacterial
  4. BM635 hydrochloride

BM635 hydrochloride 是 MmpL3 的抑制剂，具有出色的抗分歧杆菌活性，抑制结合分歧杆菌 H37Rv 的 MIC50 值为 0.08 μM。BM635 hydrochloride 相对于游离 BM635 在体内暴露量增加了一倍。

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BM635 hydrochloride Chemical Structure

BM635 hydrochloride Chemical Structure

CAS No. : 2748337-90-6

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规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

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BM635 hydrochloride 的其他形式现货产品:

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BM635 hydrochloride 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

BM635 hydrochloride is a MmpL3 inhibitor with outstanding anti-mycobacterial activity. BM635 hydrochloride has an MIC50 of 0.08 μM against M.tuberculosis H37Rv. BM635 hydrochloride doubles the in vivo exposure with respect to the free base BM635[1].

IC50 & Target

MIC50: 0.08 μM (M. tuberculosis H37Rv)[1]
体内研究
(In Vivo)

BM635 hydrochloride (oral administration; 50 mg/Kg) results in gradual elevations in blood up to a Cmax of 579.1 ng/ml with Tmax of 3 hour. It doubles the in vivo exposure with respect to the free base BM635 in C57BL/6J mice[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

428.97

Formula

C25H30ClFN2O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

BM635 hydrochloride 相关分类

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  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BM6352748337-90-6BM 635BM-635Bacterialanti-mycobacterialM.tuberculosisMycobacteriumInhibitorinhibitorinhibit

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产品名称：
BM635 hydrochloride
目录号：
HY-109587A
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