2. Neuronal Signaling
  3. CaMK
  4. CaMKI(299-320)

CaMKI(299-320)  (Synonyms: Calmodulin-Dependent Protein Kinase I (299-320) Binding Domain)

目录号: HY-P10316
产品使用指南

摩尔计算器

CaMKI (299-320) 是指钙/钙调蛋白依赖性蛋白激酶 I (Calcium/calmodulin-dependent protein kinase I，简称 CaMKI) 的第 299 至 320 位氨基酸残基组成的肽段。CaMKI (299-320) 作为蛋白激酶，与 Ca2+–CaM 具有高亲和力 (Kd≤1 nM)，能够磷酸化特定的底物蛋白，从而调节它们的活性。CaMKI (299-320) 包含了 CaM 结合域和自我抑制域，CaMKI (299-320) 可用于细胞生理过程的研究，包括细胞增殖，分化和凋亡 (apoptosis) 。

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Custom Peptide Synthesis

CaMKI(299-320) Chemical Structure

CaMKI(299-320) Chemical Structure

CAS No. : 205598-38-5

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CaMKI(299-320) 相关抗体

Top Publications Citing Use of Products

查看 CaMK 亚型特异性产品:

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CaMK III CaMK II

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CaMKI (299-320) refers to a peptide consisting of residues 299-320 of Calcium/calmodulin-dependent protein kinase I (CaMKI). CaMKI (299-320), as a protein kinase, has a high affinity interaction with Ca2+-CAM (Kd≤1 nM≤1 nM), which can phosphorylate specific substrate proteins, thereby regulating their activity. CaMKI (299-320) contains the CAM-binding domain and the self-inhibition domain, and CaMKI (299-320) can be used to study cell physiological processes, including cell proliferation, differentiation, and apoptosis[1].

分子量

2599.07

Formula

C116H192N38O28S
CAS 号
Sequence

Ala-Lys-Ser-Lys-Trp-Lys-Gln-Ala-Phe-Asn-Ala-Thr-Ala-Val-Val-Arg-His-Met-Arg-Lys-Leu-Gln
Sequence Shortening

AKSKWKQAFNATAVVRHMRKLQ
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

CaMKI(299-320) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CaMKI(299-320)205598-38-5Calmodulin-Dependent Protein Kinase I (299-320) Binding DomainCaMKCalmodulin-dependent protein kinasesCalmodulin-dependent kinasesCAMprotein kinasepeptidecell physiological processesInhibitorinhibitorinhibit

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