1. Cell Cycle/DNA Damage Protein Tyrosine Kinase/RTK
  2. STK33 CDK RET
  3. CDD-2807

CDD-2807 是一种丝氨酸/苏氨酸激酶 33 (STK33) 抑制剂,IC50 为 9.2 nM。CDD-2807 小鼠无明显毒性,可穿过血睾屏障而不会在脑中蓄积。CDD-2807 可产生可逆的避孕效果,具有开发男性避孕药的潜力。

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CDD-2807 Chemical Structure

CDD-2807 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CDD-2807 is an inhibitor for serine/threonine kinase 33 (STK33) with IC50 of 9.2 nM. CDD-2807 exhibits no significant toxicity in mice and can cross the blood-testis barrier without accumulating in the brain. CDD-2807 induces a reversible contraceptive effect and has potential for the development of the male contraceptive[1].

IC50 & Target

STK33

9.2 nM (IC50)

CLK4

85 nM (IC50)

CLK2

101 nM (IC50)

CLK1

116 nM (IC50)

RET

363 nM (IC50)

分子量

446.54

Formula

C29H26N4O

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
CDD-2807
目录号:
HY-162565
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