2. Cell Cycle/DNA Damage
  3. CDK
  4. CDK4/6-IN-12

CDK4/6-IN-12 是一种有效的周期蛋白依赖性激酶 4/6 抑制剂。CDK4/6-IN-12 对 CDK4 和 CDK6 具有酶抑制活性，IC50 值分别为 592.3 nM 和 3090 nM。 CDK4/6-IN-12 可用于癌症的研究。

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CDK4/6-IN-12 Chemical Structure

CDK4/6-IN-12 Chemical Structure

CAS No. : 2445205-24-1

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CDK4/6-IN-12 相关抗体

Top Publications Citing Use of Products

查看 CDK 亚型特异性产品:

查看所有亚型
CDK1 CDK2 CDK3 CDK4 CDK5 CDK6 CDK7 CDK8 CDK9 CDK11 CDK12 CDK13 CDK14 CDK16 CDK19 CDC CLK Pho85

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CDK4/6-IN-12 is a potent cyclin-dependent kinase 4/6 (CDK4/6) inhibitor. CDK4/6-IN-12 has enzymatic inhibitory activity for CDK4 and CDK6 with IC50 of 592.3 nM and 3090 nM, respectively. CDK4/6-IN-12 can be used for the research of cancer[1].

IC50 & Target[1]

CDK4

592.3 nM (IC50)

CDK6

3090 nM (IC50)

体外研究
(In Vitro)

CDK4/6-IN-12 (compound 4a) inhibits CDK4 and CDK6 with IC50 of 592.3 nM and 3090 nM, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

CDK4/6-IN-12 相关抗体:
分子量

238.25

Formula

C12H10N6
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

CDK4/6-IN-12 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

CDK4/6-IN-122445205-24-1CDKCyclin dependent kinasecyclin-dependent kinases (CDKs)CDK4/6antitumorcancerInhibitorinhibitorinhibit

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