2. Cell Cycle/DNA Damage
  3. DNA/RNA Synthesis
  4. CHIKV-IN-3

CHIKV-IN-3 是一种有效的针对 CHIKV-122508 和 CHIKV-6708 的低通道抑制剂，其 EC50 值分别为 1.55 和 0.14 µM。CHIKV-IN-3 作用于宿主细胞以干扰病毒复制。CHIKV-IN-3 表现出极小的细胞毒性 (CC50 > 100 µM)。预防作用。

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Custom Peptide Synthesis

CHIKV-IN-3 Chemical Structure

CHIKV-IN-3 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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Customer Review

CHIKV-IN-3 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CHIKV-IN-3 is a potent against two low-passage CHIKV inhibitor with EC50 values of 1.55 and 0.14 µM for CHIKV-122508 and CHIKV-6708, respectively. CHIKV-IN-3 acts on the host cells to interfere with the viral replication. CHIKV-IN-3 displays minimal cytotoxic liability(CC50 > 100 µM). Prophylactic effect[1].

IC50 & Target

EC50: 1.55 µM (CHIKV-122508); 0.14 µM (CHIKV-6708)[1]
体外研究
(In Vitro)

CHIKV-IN-3 (compound (E)-42; HeLa CCL2 cells; 0.1-100 µM; 24 hours) inhibits the Chikungunya virus (CHIKV) replication with an EC50 of 1.55 µM and demonstrates low cytotoxicity (CC50=129.6 µM)[1]. CHIKV-IN-3 (HeLa CCL2 cells; 20, 40, 80 µM; 24 hours) shows the highest degree of inhibition with approximately 3.9-log reduction in viral titre (ca. 99.99% inhibition) at 80 µM[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

CHIKV-IN-3 相关抗体:

Cell Cytotoxicity Assay[1]

Cell Line: HeLa CCL2 cells, HeLa CCL2 cells infected with CHIKV-122508
Concentration: 0.1-100 µM
Incubation Time: 24 hours
Result: Inhibited the CHIKV replication with an EC50 of 1.55 µM and demonstrated low cytotoxicity(CC50=129.6 µM)
分子量

383.95

Formula

C24H30ClNO
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

CHIKV-IN-3 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CHIKV-IN-3DNA/RNA Synthesisantivirallow cytotoxicityHeLa CCL2 cellschikungunya virus infectionviral replicationInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-144334
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