2. Metabolic Enzyme/Protease Apoptosis Cell Cycle/DNA Damage Neuronal Signaling GPCR/G Protein Immunology/Inflammation
  3. Endogenous Metabolite Apoptosis DNA/RNA Synthesis α-synuclein Lipoxygenase Opioid Receptor Interleukin Related TNF Receptor
  4. Cuminaldehyde (Standard)

Cuminaldehyde (Standard)  (Synonyms: 4-异丙基苯甲醛 (Standard))

目录号: HY-Y0790R 纯度: ≥98%
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摩尔计算器

Cuminaldehyde (Standard) 是 Cuminaldehyde 的分析标准品。本产品用于研究及分析应用。Cuminaldehyde 是 Cuminum cyminum 的主要成分，具有多种生物活性，包括抗炎、抗癌、抗糖尿病、抗损伤、抗神经病变和抑菌作用。Cuminaldehyde 是醛糖还原酶 (IC50=0.00085 mg/mL) 和 α-葡萄糖苷酶 (IC50=0.5 mg/mL) 的抑制剂。Cuminaldehyde 可以调节 α-突触核蛋白α-SN纤维。通过靶向拓扑异构酶 I 和 II，Cuminaldehyde 可以诱导结肠腺癌细胞凋亡 (apoptosis)。此外，Cuminaldehyde 还通过抑制脂氧合酶 (lipoxygenase) 发挥抗炎活性。Cuminaldehyde 对黄曲霉生长和黄曲霉毒素 B1 (AFB1) 的生物合成均有较强的抑制作用。Cuminaldehyde 可通过参与阿片受体 (opioid Receptor)、L-精氨酸/NO/cGMP 通路及抗炎作用发挥抗损伤和抗神经病变作用。Cuminaldehyde 在神经退行性疾病、癌症、糖尿病和神经性疼痛性疾病的研究中具有潜在应用价值。

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Cuminaldehyde (Standard) Chemical Structure

Cuminaldehyde (Standard) Chemical Structure

CAS No. : 122-03-2

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生物活性

Cuminaldehyde (Standard) is the analytical standard of Cuminaldehyde. This product is intended for research and analytical applications. Cuminaldehyde is the main component of Cuminum cyminum and has multiple biological activities, including anti-inflammatory, anti-cancer, anti-diabetic, anti-injury, anti-neuropathy and antibacterial effects. Cuminaldehyde is an inhibitor of aldose reductase (IC50= 0.00085 mg/mL) and α-glucosidase (IC50=0.5 mg/mL). Cuminaldehyde can modulate α-synuclein fibrils. Cuminaldehyde can induce apoptosis in colon adenocarcinoma cells by targeting topoisomerase I and II. In addition, Cuminaldehyde also exerts anti-inflammatory activity by inhibiting lipoxygenase. Cuminaldehyde has a strong inhibitory effect on the growth of Aspergillus flavus and the biosynthesis of aflatoxin B1 (AFB1). Cuminaldehyde can exert anti-injury and anti-neuropathy effects by participating in opioid receptors, L-arginine/NO/cGMP pathways and anti-inflammatory effects. Cuminaldehyde has potential application value in the research of neurodegenerative diseases, cancer, diabetes and neuropathic pain diseases.

分子量

148.20

Formula

C10H12O
CAS 号
中文名称

4-异丙基苯甲醛 (Standard)
结构分类
初始来源
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Cuminaldehyde (Standard) 相关分类

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cuminaldehyde (Standard)122-03-24-异丙基苯甲醛 (Standard)Endogenous MetaboliteApoptosisDNA/RNA Synthesisα-synucleinLipoxygenaseOpioid ReceptorInterleukin RelatedTNF Receptorα-SynLOXILTumor Necrosis Factor ReceptorTNFRInhibitorinhibitorinhibit

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