2. GPCR/G Protein
  3. Angiotensin Receptor
  4. (D-Pro7)-Angiotensin I/II (1-7)

(D-Pro7)-Angiotensin I/II (1-7) 是一种选择性的、基于肽的 Angiotensin-(1-7) 拮抗剂。(D-Pro7)-Angiotensin I/II (1-7) 强效阻断 Ang-(1-7) 的多种生物学效应。(D-Pro7)-Angiotensin I/II (1-7) 抑制微注射 Ang-(1-7) 至腹侧延髓前外侧区 (RVLM) 诱导的高血压反应，并消除小鼠的内皮依赖性血管松弛。(D-Pro7)-Angiotensin I/II (1-7) 可用于心血管疾病研究。

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(D-Pro7)-Angiotensin I/II (1-7)

(D-Pro7)-Angiotensin I/II (1-7) Chemical Structure

CAS No. : 586962-44-9

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规格 价格 是否有货
1 mg ￥765
询问价格 & 货期
5 mg ￥2250
询问价格 & 货期
10 mg ￥3600
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(D-Pro7)-Angiotensin I/II (1-7) 相关抗体

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查看 Angiotensin Receptor 亚型特异性产品:

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AT1 Receptor AT2 Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(D-Pro7)-Angiotensin I/II (1-7) is a selective, peptide-based antagonist of Angiotensin-(1-7). (D-Pro7)-Angiotensin I/II (1-7) potently blocks multiple biological effects of Ang-(1-7). (D-Pro7)-Angiotensin I/II (1-7) inhibits the hypertensive response induced by microinjection of Ang-(1-7) into the rostral ventrolateral medulla (RVLM) and abolishes the endothelium-dependent vasorelaxation of mouse. (D-Pro7)-Angiotensin I/II (1-7) can be used for the study of cardiovascular diseases[1].

分子量

899.00

Formula

C41H62N12O11
CAS 号
Sequence

Asp-Arg-Val-Tyr-Ile-His-{d-Pro}
Sequence Shortening

DRVYIH-{d-Pro}
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

(D-Pro7)-Angiotensin I/II (1-7) 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(D-Pro7)-Angiotensin I/II (1-7)586962-44-9Angiotensin Receptorcardiovascular diseasesAngiotensin-(1-7)hypertensive responseInhibitorinhibitorinhibit

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