1. Others Metabolic Enzyme/Protease
  2. Thrombin Isotope-Labeled Compounds
  3. Dabigatran etexilate-d11

Dabigatran etexilate-d11  (Synonyms: BIBR 1048-d11)

目录号: HY-W705434
产品使用指南 技术支持

Dabigatran etexilate-d11 (BIBR 1048-d11) 是 Dabigatran etexilate (HY-10274) 的氘代物。Dabigatran etexilate (BIBR 1048) 是具有口服活性的 Dabigatran (一种凝血酶抑制剂) 的前体。Dabigatran etexilate 具有抗凝作用,可以预防心房颤动引起的静脉血栓栓塞和中风。

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Dabigatran etexilate-d<sub>11</sub>

Dabigatran etexilate-d11 Chemical Structure

CAS No. : 2469006-94-6

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Dabigatran etexilate-d11 (BIBR 1048-d11) is the deuterium labeled Dabigatran etexilate (HY-10274). Dabigatran etexilate (BIBR 1048) is an orally active proagent of Dabigatran (a direct inhibitor of thrombin). Dabigatran etexilate has anticoagulant effects and is used for the prophylaxis of venousthromboembolism and stroke due to atrial fibrillation[1].

产品应用

1. 该化合物可作为示踪剂。
2. 该化合物可作为 NMR、GC-MS 或 LC-MS 分析中的内标品,用于定量分析。

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

638.80

Formula

C34H30D11N7O5

CAS 号
非标记 CAS
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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