2. Cell Cycle/DNA Damage
  3. Topoisomerase
  4. Diflomotecan

Diflomotecan  (Synonyms: BN 80915)

目录号: HY-13611
产品使用指南

摩尔计算器

Diflomotecan (BN 80915) 是一种有效且具有口服活性的拓扑异构酶 I (topoisomerase I) 抑制剂。与其他已建立的化合物相比，Diflomotecan (BN 80915) 能增强血浆稳定性，同时具有优越的临床前抗肿瘤活性。

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Diflomotecan Chemical Structure

Diflomotecan Chemical Structure

CAS No. : 220997-97-7

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Diflomotecan 相关抗体

Top Publications Citing Use of Products

查看 Topoisomerase 亚型特异性产品:

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Topoisomerase Topo I Topo II

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Diflomotecan (BN 80915) is a potent and orally active inhibitor of topoisomerase I. Diflomotecan (BN 80915) causes enhanced plasma stability and has the superior preclinical anti-tumour activity compared with other established compounds[1][2].

IC50 & Target

topoisomerase I[1]
Clinical Trial
分子量

398.36

Formula

C21H16F2N2O4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Diflomotecan 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Diflomotecan220997-97-7BN 80915BN80915BN-80915Topoisomeraseoraltopoisomerase Iplasma stabilityanti-tumourpreclinicalInhibitorinhibitorinhibit

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