2. 天然产物
  3. 疾病研究领域 植物 酚类
  4. 姜科 癌症 多酚类
  5. 姜黄
  6. (E/Z)-Demethoxycurcumin

(E/Z)-Demethoxycurcumin  (Synonyms: (E/Z)-去甲氧基姜黄素; p-Hydroxycinnamoyl-feruloylmethane)

目录号: HY-N0006A 纯度: ≥98.0%
COA 产品使用指南

摩尔计算器

(E/Z)-Demethoxycurcumin (p-Hydroxycinnamoyl-feruloylmethane) 是从姜黄属植物中分离出的姜黄素，具有抗凝血活性。

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(E/Z)-Demethoxycurcumin Chemical Structure

(E/Z)-Demethoxycurcumin Chemical Structure

CAS No. : 24939-17-1

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规格 价格 是否有货 数量
5 mg ￥2400
In-stock
10 mg ￥3400
In-stock
50 mg   询价  
100 mg   询价  

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Customer Review

Other Forms of (E/Z)-Demethoxycurcumin:

(E/Z)-Demethoxycurcumin 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(E/Z)-Demethoxycurcumin (p-Hydroxycinnamoyl-feruloylmethane) is a curcuminoid isolated from curcuma species, with anticoagulative active[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A-431 IC50
> 100 μM
Compound: DC
Cytotoxicity against human A431 cells preincubated for 4 hrs followed by incubation in compound free media for 24 hrs by MTT assay
Cytotoxicity against human A431 cells preincubated for 4 hrs followed by incubation in compound free media for 24 hrs by MTT assay
[PMID: 29605808]
A549 IC50
28.2 μM
Compound: DC
Cytotoxicity against human A549 cells preincubated for 4 hrs followed by incubation in compound free media for 24 hrs by MTT assay
Cytotoxicity against human A549 cells preincubated for 4 hrs followed by incubation in compound free media for 24 hrs by MTT assay
[PMID: 29605808]
DLD-1 IC50
> 40 μM
Compound: DC
Cytotoxicity against human DLD1 cells preincubated for 4 hrs followed by incubation in compound free media for 24 hrs by MTT assay
Cytotoxicity against human DLD1 cells preincubated for 4 hrs followed by incubation in compound free media for 24 hrs by MTT assay
[PMID: 29605808]
MCF7 IC50
92.1 μM
Compound: DC
Cytotoxicity against human MCF7 cells preincubated for 4 hrs followed by incubation in compound free media for 24 hrs by MTT assay
Cytotoxicity against human MCF7 cells preincubated for 4 hrs followed by incubation in compound free media for 24 hrs by MTT assay
[PMID: 29605808]
MDA-MB-231 IC50
9 mM
Compound: DMC
Increase in MMP3 level in human MDA-MB-231 cells after 24 hrs by ELISA
Increase in MMP3 level in human MDA-MB-231 cells after 24 hrs by ELISA
[PMID: 31336310]
WRL68 IC50
26.3 μM
Compound: DC
Cytotoxicity against human WRL68 cells preincubated for 4 hrs followed by incubation in compound free media for 24 hrs by MTT assay
Cytotoxicity against human WRL68 cells preincubated for 4 hrs followed by incubation in compound free media for 24 hrs by MTT assay
[PMID: 29605808]
分子量

338.35

Formula

C20H18O5
CAS 号
性状

固体

颜色

Yellow to orange

中文名称

(E/Z)-去甲氧基姜黄素
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性数据
细胞实验： 

DMSO 中的溶解度 : ≥ 100 mg/mL (295.55 mM; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

* "≥" means soluble, but saturation unknown.

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.9555 mL 14.7776 mL 29.5552 mL
5 mM 0.5911 mL 2.9555 mL 5.9110 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料

纯度: ≥98.0%

COA (188 KB) HNMR (217 KB)

产品使用指南 (1538 KB)
参考文献

(E/Z)-Demethoxycurcumin 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9555 mL 14.7776 mL 29.5552 mL 73.8880 mL
5 mM 0.5911 mL 2.9555 mL 5.9110 mL 14.7776 mL
10 mM 0.2956 mL 1.4778 mL 2.9555 mL 7.3888 mL
15 mM 0.1970 mL 0.9852 mL 1.9703 mL 4.9259 mL
20 mM 0.1478 mL 0.7389 mL 1.4778 mL 3.6944 mL
25 mM 0.1182 mL 0.5911 mL 1.1822 mL 2.9555 mL
30 mM 0.0985 mL 0.4926 mL 0.9852 mL 2.4629 mL
40 mM 0.0739 mL 0.3694 mL 0.7389 mL 1.8472 mL
50 mM 0.0591 mL 0.2956 mL 0.5911 mL 1.4778 mL
60 mM 0.0493 mL 0.2463 mL 0.4926 mL 1.2315 mL
80 mM 0.0369 mL 0.1847 mL 0.3694 mL 0.9236 mL
100 mM 0.0296 mL 0.1478 mL 0.2956 mL 0.7389 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(E/Z)-Demethoxycurcumin24939-17-1p-Hydroxycinnamoyl-feruloylmethane(E/Z)-去甲氧基姜黄素OthersInhibitorinhibitorinhibit

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