1. 一站式药筛
  2. 化合物库
  3. 天然产物化合物库系列
  4. 中药相关化合物库
  5. 活血化瘀中药单体库
活血化瘀中药单体库 - PBCRBS Traditional Chinese Medicine Compound Library

Cat. No.: HY-L193

从古至今,活血化瘀(Promoting blood circulation for removing blood stasis, PBCRBS)是传统中医药学和中西医结合药学领域中最活跃的研究内容之一。川芎、桃仁、红花、姜黄等都是常见的活血化瘀中药。已有研究表明,活血化瘀类中药的作用机制主要在于活其血脉(改善心脑血管功能、血液理化性状、血小板及凝血系统等生理功能)、化其瘀滞(抗心肌缺血、脑缺血,抑制血小板聚集,抗凝、抗血栓形成等)。 不仅如此,活血化瘀药物具有抗感染,抑制炎症反应,调节免疫功能,抑制免疫反应,抑制组织异常增殖等功能。因此,活血化瘀类中药在其他疾病研究领域也有极高的研究价值。

MCE 收录了 1,062 个来自于百余种活血化瘀中药来源的单体成分,可应用于中药成分研究、药物开发与机制类研究中。

我们将在明确您的产品用途后,向符合资质的客户通过定制合成服务的方式提供 MCE 活血化瘀中药单体库,我们为该库中的所有产品提供溶液包装或粉末包装。溶液包装中,1,030 个产品以 10 mM 浓度提供,26 个产品以 2 mM 浓度提供,6 个产品以 3 mg/mL 浓度提供。

溶液包装中,我们对于溶液状态稳定且溶解度不低于 10 mM 的产品,提供 10 mM 溶液;对于溶液状态稳定且溶解度介于 2~10 mM 的产品,我们提供 2 mM 溶液;对于溶液状态稳定、分子量不确定且溶解度不低于 3 mg/mL产品,我们提供 3 mg/mL 溶液。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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Compound Screening Libraries

Top Publications Citing Use of MCE Products

MCE 顾客使用化合物库产品发表的文献

  • 生物活性
  • 产品详情
  • 产品资料
  • 化合物库组成

活性描述 & 特点

Biological Activity

•   A unique collection of 1,062 PBCRBS Traditional Chinese Medicine for high throughput screening (HTS) and high content screening (HCS).

•   A useful tool for the discovery of compounds for diseases.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.

•   Structurally diverse, bioactive, and cell permeable.

•   More detailed compound information with structure, IC50, and other chemical & biological data.

•   High purity and quality validated by NMR and LC/MS.

•   All compounds are in stock and continuously updated.

产品详情

Product Details

Formulation:

A collection of 1,062 PBCRBS Traditional Chinese Medicine supplied as pre-dissolved Solutions or Solid.
Solution: 1,030 compounds supplied in 10 mM solution, 26 compounds supplied in 2 mM solution, 6 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice or dry ice

化合物库组成

Composition

COX (40)

PPAR (16)

Akt (15)

HIV (15)

PI3K (13)

ERK (11)

MMP (10)

EGFR (8)

HSV (8)

JNK (7)

STAT (7)

HSP (6)

mTOR (6)

PKC (6)

AMPK (5)

JAK (5)

PARP (5)

FGFR (4)

HBV (3)

Wnt (3)

AP-1 (2)

DYRK (2)

FAAH (2)

FAK (2)

FXR (2)

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  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack

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    产品名称:
    PBCRBS Traditional Chinese Medicine Compound Library
    目录号:
    HY-L193
    需求量: