2. Metabolic Enzyme/Protease
  3. Glucosidase
  4. EB-0176

EB-0176 是 ER α-葡萄糖苷酶 (α-Glu) I 和 II 的有效抑制剂，IC50s 值分别为 0.6439 和 0.0011 μM。EB-0176 是一种 N-取代的缬草胺衍生物，具有广谱抗病毒作用。EB-0176 具有研究针对现有和新兴病毒的广谱活性分子的潜力。

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EB-0176 Chemical Structure

EB-0176 Chemical Structure

CAS No. : 2758314-64-4

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EB-0176 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

EB-0176 is a potent inhibitor of ER α-glucosidases (α-Glu) Iand II with IC50s of 0.6439 and 0.0011 μM, respectively. EB-0176 is a N-substituted derivative of valiolamine with broad-spectrum antiviral. EB-0176 has the potential for the reseach of broad-spectrum agent against the existing and emerging viruses[1].

IC50 & Target

Glucosidase[1]
Endoplasmic Reticulum α-Glucosidases I and II inhibitor[1]
细胞效力
(Cellular Effect)
Cell Line Type Value Description References
Vero CC50
761.5 μM
Compound: EB-0176
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability incubated for 3 to 5 days by Cell titer-glo luminescent assay
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability incubated for 3 to 5 days by Cell titer-glo luminescent assay
[PMID: 34870992]
分子量

491.54

Formula

C23H33N5O7
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

EB-0176 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EB-01762758314-64-4EB0176EB 0176GlucosidaseERα-glucosidasealiolaminebroad-spectrumantiviralInhibitorinhibitorinhibit

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目录号：
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