RANBP9 - RAN binding protein 9 Gene

中文名称：RAN 结合蛋白 9

种属: Homo sapiens

同用名: BPM-L; BPM90; RANBPM; RanBP7

基因 ID: 10048 | 基因类型: protein coding

关于 RANBP9

Cytogenetic location: 6p23 Genomic coordinates (GRCh38): 6:13,621,498-13,711,835 (from NCBI)

This gene has 2 transcripts (splice variants), 233 orthologues and 3 paralogues. Broad expression in testis (RPKM 72.2), esophagus (RPKM 38.9) and 23 other tissues.

功能概要

该基因编码一种结合 RAN 的蛋白质，RAN 是一种属于 Ras 超家族的小 GTP 结合蛋白，对于 RNA 和蛋白质通过核孔复合体的转运至关重要。该基因编码的蛋白质也已被证明与其他几种蛋白质相互作用，包括 met 原癌基因、同源域相互作用蛋白激酶 2、雄激素受体和细胞周期蛋白依赖性激酶 11。[RefSeq 提供，2008 年 7 月]

This gene encodes a protein that binds RAN, a small GTP binding protein belonging to the Ras superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The protein encoded by this gene has also been shown to interact with several Other proteins, including met proto-oncogene, homeodomain interacting protein kinase 2, Androgen Receptor, and cyclin-dependent kinase 11. [provided by RefSeq, Jul 2008]

RANBP9 基因产物(1)

mRNA	Protein	Name
NM_005493.3	NP_005484.2	ran-binding protein 9

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables enzyme binding	IPI IPI: 通过物理相互作用推断	17087506	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	12220523	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in negative regulation of ERK1 and ERK2 cascade	IMP IMP: 通过突变表型推断	23118896	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in cytoplasm	IDA IDA: 通过直接分析推断	15381419	GOA
located in nucleus	IDA IDA: 通过直接分析推断	12220523	GOA
part of ubiquitin ligase complex	IDA IDA: 通过直接分析推断	29911972	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

RANBP9 蛋白结构

SPRY

LisH

CLTH

0
200
400
600
729 a.a.

蛋白主名

其他名称

ran-binding protein 9

Ran Binding Protein in the Microtubule organizing center

RANBP9 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	RANBP9	Q96S59	OPRM1	Homo sapiens	P35372	Y2H	23840749
种属内	RANBP9	Q96S59	OPRM1	Homo sapiens	P35372	Pull Down	23840749
种属内	RANBP9	Q96S59	S100A7	Homo sapiens	P31151	Y2H	12421467
种属内	RANBP9	Q96S59	PPP1CC	Homo sapiens	P36873-2	Y2H	21382349
种属内	RANBP9	Q96S59	DISC1	Homo sapiens	Q9NRI5	Y2H	12812986
种属内	RANBP9	Q96S59	DYRK1B	Homo sapiens	Q9Y463	Pull Down	14500717
种属内	RANBP9	Q96S59	ENTPD1	Homo sapiens	P49961	Anti Bait CoIP	16478441
种属内	RANBP9	Q96S59	ENTPD1	Homo sapiens	P49961	Anti Tag CoIP	16478441

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Lissencephaly

Pachygyria	Broad Gyri Of Cerebrum
Large Gyri Of Cerebrum	Macrogyria

Lissencephaly 1

LIS1	Classic Lissencephaly
Ils	Subcortical Laminar Heterotopia
Lissencephaly Due To Lis1 Mutation	Lissencephaly Sequence, Isolated
Lissencephaly, Classic	Pafah1b1-Related Lissencephaly
Classical Lissencephaly	Lissencephaly Type 1
Lissencephaly-1	Subcortical Band Heterotopia
Double Cortex	Lissencephaly Classic
Lissencephaly Sequence Isolated	Isolated Lissencephaly Sequence
Type 1 Lissencephaly	Lissencephaly Syndrome Type 1
SBH	Sclh
Lissencephaly, Type 1	Type I Lissencephaly

Breast Cancer

Breast Carcinoma	Male Breast Cancer
Breast Cancer, Familial	Malignant Neoplasm Of Breast
Breast Cancer, Susceptibility To	Breast Cancer, Early-Onset
Malignant Tumor Of Breast	Carcinoma Of Male Breast
Breast Cancer, Invasive Ductal	Breast Cancer, Protection Against
Breast Cancer, Somatic	Breast Cancer, Male
Breast Cancer, Lobular, Somatic	Breast Tumor
Mammary Cancer	Mammary Tumor
Malignant Neoplasm Of Male Breast	Mammary Carcinoma
Male Breast Carcinoma	Familial Cancer Of Breast
Invasive Ductal Breast Carcinoma	Breast Cancer Susceptibility
Breast Cancer, Male, Susceptibility To	Breast Cancer, Early-Onset, Susceptibility To
Malignant Tumor Of The Breast	Mammary Neoplasm
Primary Breast Cancer	Neoplasm Of Male Breast
Carcinoma Of Breast	Breast Cancer In Men
Familial Breast Cancer	Cancer Of Breast
BC	Breast Cancer Familial
Breast Cancer Familial Male	Breast Cancer, Familial Male
Breast Male Carcinoma	Breast Neoplasms
Breast Neoplasms, Male	Mammary Tumors
Mammary Carcinomas	Cancer, Breast
Cancer, Breast, Susceptibility	Invasive Breast Ductal Carcinoma
Breast Neoplasm	Susceptibility To Breast Cancer
Mammary Neoplasms	Animal Mammary Neoplasms
Primary Malignant Neoplasm Of Breast	Infiltrating Ductal Carcinoma Of Breast
Infiltrating Duct Carcinoma Of Unspecified Site	Infiltrating Ductular Carcinoma Of Unspecified Site
Invasive Breast Carcinoma Of No Special Type	Microinvasive Carcinoma Of Breast
Carcinoma With Apocrine Differentiation

Congenital Nervous System Abnormality

Congenital Neurologic Anomaly

Congenital Nervous System Disorder

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS11649	RANBP9 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Felis catus	RANBP9	VGNC	VGNC:102500
Mus musculus	RANBP9	MGD	MGI:1928741
Canis familiaris	RANBP9	VGNC	VGNC:49679
Rattus norvegicus	RANBP9	RGD	RGD:1561940
Macaca mulatta	RANBP9	VGNC	VGNC:76475
Bos taurus	RANBP9	VGNC	VGNC:33712

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

RANBP9 - RAN binding protein 9 Gene

关于 RANBP9

功能概要

RANBP9 基因产物(1)

RANBP9 蛋白结构

RANBP9 蛋白互作信息

关联疾病

直系同源

热门区域

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RANBP9 - RAN binding protein 9 Gene

关于 RANBP9

功能概要

RANBP9 基因产物(1)

RANBP9 蛋白结构

RANBP9 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z