DCAF7 - DDB1 and CUL4 associated factor 7 Gene

中文名称：DDB1 和 CUL4 相关因子 7

种属: Homo sapiens

同用名: AN11; HAN11; WDR68; SWAN-1

关于 DCAF7

功能概要

该基因编码的蛋白质具有多个 WD40 重复序列，可促进蛋白质-蛋白质相互作用，从而实现多蛋白质复合物的组装。该蛋白质已被证明可作为参与激酶信号传导的蛋白质复合物的支架蛋白。这种高度保守的基因存在于真核植物、真菌和动物中。该基因的直系同源物首先在植物中被鉴定为花青素生物合成和花色素沉着的关键调节剂。可变剪接导致多个转录本变体。[RefSeq 提供，2014 年 2 月]

This gene encodes a protein with multiple WD40 repeats which facilitate protein-protein interactions and thereby enable the assembly of multiprotein complexes. This protein has been shown to function as a scaffold protein for protein complexes involved in kinase signaling. This highly conserved gene is present in eukaryotic Plants, fungi, and Animals. The ortholog of this gene was first identified in Plants as a key regulator of anthocyanin biosynthesis and flower pigmentation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]