2. Gene
  3. SRRM1 - serine and arginine repetitive matrix 1 Gene

SRRM1 - serine and arginine repetitive matrix 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：丝氨酸和精氨酸重复矩阵 1

种属: Homo sapiens

同用名: 160-KD; POP101; SRM160

基因 ID: 10250 | 基因类型: protein coding

关于 SRRM1

Cytogenetic location: 1p36.11 Genomic coordinates (GRCh38): 1:24,643,302-24,673,281 (from NCBI)

This gene has 26 transcripts (splice variants) and 156 orthologues. Ubiquitous expression in ovary (RPKM 22.6), prostate (RPKM 22.3) and 25 other tissues.

功能概要

启用 RNA 结合活性。预计通过剪接体参与 mRNA 剪接。位于核斑点。催化步骤 2 剪接体的一部分。妊娠糖尿病的生物标志物。 [由基因组资源联盟提供，2022 年 4 月]

Enables RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Located in nuclear speck. Part of catalytic step 2 spliceosome. Biomarker of gestational diabetes. [provided by Alliance of Genome Resources, Apr 2022]

SRRM1 基因产物(35)

mRNA Protein Name
NM_001303448.2 NP_001290377.1 serine/arginine repetitive matrix protein 1 isoform 1
NM_001303449.1 NP_001290378.1 serine/arginine repetitive matrix protein 1 isoform 3
NM_001366565.1 NP_001353494.1 serine/arginine repetitive matrix protein 1 isoform 4
NM_001366566.1 NP_001353495.1 serine/arginine repetitive matrix protein 1 isoform 4
NM_001366567.1 NP_001353496.1 serine/arginine repetitive matrix protein 1 isoform 5
NM_001366568.1 NP_001353497.1 serine/arginine repetitive matrix protein 1 isoform 6
NM_001366569.1 NP_001353498.1 serine/arginine repetitive matrix protein 1 isoform 7
NM_001366570.1 NP_001353499.1 serine/arginine repetitive matrix protein 1 isoform 8
NM_001366571.1 NP_001353500.1 serine/arginine repetitive matrix protein 1 isoform 6
NM_001366572.1 NP_001353501.1 serine/arginine repetitive matrix protein 1 isoform 9
NM_001366573.1 NP_001353502.1 serine/arginine repetitive matrix protein 1 isoform 10
NM_001366575.1 NP_001353504.1 serine/arginine repetitive matrix protein 1 isoform 11
NM_001366576.1 NP_001353505.1 serine/arginine repetitive matrix protein 1 isoform 12
NM_001366577.1 NP_001353506.1 serine/arginine repetitive matrix protein 1 isoform 13
NM_001366578.1 NP_001353507.1 serine/arginine repetitive matrix protein 1 isoform 14
NM_001366581.1 NP_001353510.1 serine/arginine repetitive matrix protein 1 isoform 15
NM_001366582.1 NP_001353511.1 serine/arginine repetitive matrix protein 1 isoform 16
NM_001366584.1 NP_001353513.1 serine/arginine repetitive matrix protein 1 isoform 5
NM_001366585.1 NP_001353514.1 serine/arginine repetitive matrix protein 1 isoform 18
NM_001366586.1 NP_001353515.1 serine/arginine repetitive matrix protein 1 isoform 19
NM_001366587.1 NP_001353516.1 serine/arginine repetitive matrix protein 1 isoform 20
NM_001366588.1 NP_001353517.1 serine/arginine repetitive matrix protein 1 isoform 21
NM_001366589.1 NP_001353518.1 serine/arginine repetitive matrix protein 1 isoform 22
NM_001366590.1 NP_001353519.1 serine/arginine repetitive matrix protein 1 isoform 10
NM_001366591.1 NP_001353520.1 serine/arginine repetitive matrix protein 1 isoform 20
NM_001366592.1 NP_001353521.1 serine/arginine repetitive matrix protein 1 isoform 23
NM_001366593.1 NP_001353522.1 serine/arginine repetitive matrix protein 1 isoform 18
NM_001366594.1 NP_001353523.1 serine/arginine repetitive matrix protein 1 isoform 14
NM_001366595.1 NP_001353524.1 serine/arginine repetitive matrix protein 1 isoform 24
NM_001366596.1 NP_001353525.1 serine/arginine repetitive matrix protein 1 isoform 25
NM_001366597.1 NP_001353526.1 serine/arginine repetitive matrix protein 1 isoform 26
NM_001366598.1 NP_001353527.1 serine/arginine repetitive matrix protein 1 isoform 9
NM_001366599.1 NP_001353528.1 serine/arginine repetitive matrix protein 1 isoform 5
NM_001366600.1 NP_001353529.1 serine/arginine repetitive matrix protein 1 isoform 6
NM_005839.4 NP_005830.2 serine/arginine repetitive matrix protein 1 isoform 2
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
23602568 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of catalytic step 2 spliceosome IDA
IDA: 通过直接分析推断
11991638 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SRRM1 蛋白结构

PWI

PWI: PWI domain (45 - 116)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 904 a.a.
蛋白主名 其他名称

serine/arginine repetitive matrix protein 1

SR-related nuclear matrix protein of 160 kDa

SRRM1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra SRRM1 Q8IYB3 CLK2 Homo sapiens P49760-3
Validated Y2H
26871637
Intra SRRM1 Q8IYB3 CLK2 Homo sapiens P49760-3
Y2H Array
26871637
Intra SRRM1 Q8IYB3 CLK2 Homo sapiens P49760-3
Y2H Prey Pooling
26871637
Intra SRRM1 Q8IYB3 SRRM4 Homo sapiens A7MD48
Y2H Array
32296183
Intra SRRM1 Q8IYB3 SRRM4 Homo sapiens A7MD48
Y2H Prey Pooling
32296183
Intra SRRM1 Q8IYB3 CLK2 Homo sapiens P49760
Y2H Prey Pooling
26871637
Intra SRRM1 Q8IYB3 CLK2 Homo sapiens P49760
Y2H Prey Pooling
25416956
Intra SRRM1 Q8IYB3 CLK2 Homo sapiens P49760
Validated Y2H
26871637
Intra SRRM1 Q8IYB3 CLK2 Homo sapiens P49760
Y2H Array
26871637
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13786 SRRM1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus SRRM1 RGD RGD:1311258
Mus musculus SRRM1 MGD MGI:1858303
Bos taurus SRRM1 VGNC VGNC:35294
Macaca mulatta SRRM1 VGNC VGNC:100149
Felis catus SRRM1 VGNC VGNC:107640
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