2. Gene
  3. Cd276 - CD276 antigen Gene

Cd276 - CD276 antigen Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: B7h3; B7RP-2; 6030411F23Rik

基因 ID: 102657 | 基因类型: protein coding

关于 Cd276

功能概要

Enables identical protein binding activity and signaling receptor binding activity. Acts upstream of or within several processes, including positive regulation of osteoblast differentiation; regulation of T cell proliferation; and regulation of cytokine production. Located in external side of plasma membrane. Is expressed in several structures, including embryo endoderm; genitourinary system; hemolymphoid system; liver; and musculoskeletal system. Orthologous to human CD276 (CD276 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd276 基因产物(1)

mRNA Protein Name
NM_133983.4 NP_598744.1 CD276 antigen precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
23583036 MGI
enables signaling receptor binding IDA
IDA: 通过直接分析推断
12055244 MGI
enables signaling receptor binding IMP
IMP: 通过突变表型推断
12925852 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of T cell proliferation IDA
IDA: 通过直接分析推断
12925852 MGI
acts upstream of T cell proliferation IMP
IMP: 通过突变表型推断
12925852 MGI
acts upstream of or within negative regulation of T cell proliferation IDA
IDA: 通过直接分析推断
12925852 MGI
acts upstream of or within negative regulation of T cell proliferation IMP
IMP: 通过突变表型推断
12925852 MGI
acts upstream of or within negative regulation of inflammatory response IMP
IMP: 通过突变表型推断
12925852 MGI
acts upstream of or within negative regulation of interleukin-2 production IDA
IDA: 通过直接分析推断
12925852 MGI
acts upstream of or within negative regulation of type II interferon production IDA
IDA: 通过直接分析推断
12925852 MGI
acts upstream of or within negative regulation of type II interferon production IMP
IMP: 通过突变表型推断
12925852 MGI
acts upstream of or within positive regulation of T cell proliferation IMP
IMP: 通过突变表型推断
16751379 MGI
acts upstream of or within positive regulation of bone mineralization IMP
IMP: 通过突变表型推断
15317945 MGI
acts upstream of or within positive regulation of interleukin-2 production IMP
IMP: 通过突变表型推断
16751379 MGI
acts upstream of or within positive regulation of osteoblast differentiation IMP
IMP: 通过突变表型推断
15317945 MGI
acts upstream of or within regulation of immune response IMP
IMP: 通过突变表型推断
12925852 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
12925852 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

CD276 antigen

B7 homolog 3

B7-H3

costimulatory molecule

Cd276 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Cd276 Q8VE98 Cd276 Mus musculus Q8VE98
GMS
23583036
种属内
Cd276 Q8VE98 Cd276 Mus musculus Q8VE98
X-Ray Diffraction
23583036
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 Cd276 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7639 CD276/B7-H3 Protein, Mouse (HEK293, His) Q8VE98 (V29-F244) ≥95%

相关产品

Clinical Phase
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P99157 Omburtamab Inhibitor 98.27% Phase 2
Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02220 CD276 Human Pre-designed siRNA Set A Pre-designed Sets / 否
抗体抑制剂 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P99740 Mirzotamab Inhibitor 99.45% 否
HY-P990340 Anti-B7-H3/CD276 Antibody Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cd276 NCBI NCBI:80381
Macaca fascicularis Cd276 NCBI NCBI:102131295
Rattus norvegicus Cd276 NCBI NCBI:315716
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