1. Gene
  2. PNMA2 - PNMA family member 2 Gene

PNMA2 - PNMA family member 2 Gene

中文名称:PNMA 家族成员 2

种属: Homo sapiens

同用名: MA2; MM2; RGAG2

基因 ID: 10687 | 基因类型: protein coding

关于 PNMA2

Cytogenetic location: 8p21.2 Genomic coordinates (GRCh38): 8:26,504,701-26,513,872 (from NCBI)

This gene has 8 transcripts (splice variants), 579 orthologues and 13 paralogues. Biased expression in brain (RPKM 63.2), adrenal (RPKM 6.1) and 1 other tissue.

功能概要

预计参与细胞凋亡过程的正向调节。预测位于核仁中。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to be involved in positive regulation of apoptotic process. Predicted to be located in nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

PNMA2 基因产物(1)

mRNA Protein Name
NM_007257.6 NP_009188.1 paraneoplastic antigen Ma2
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
17474147 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

PNMA2 蛋白结构

PNMA

PNMA: PNMA (1 - 329)

  • 0
  • 100
  • 200
  • 300
  • 364 a.a.
蛋白主名 其他名称

paraneoplastic antigen Ma2

40 kDa neuronal protein

PNMA2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
PNMA2 Q9UL42 RTP5 Homo sapiens Q14D33 25416956
种属内
PNMA2 Q9UL42 PRPF31 Homo sapiens Q8WWY3 25416956
种属内
PNMA2 Q9UL42 PRPF31 Homo sapiens Q8WWY3 25416956
种属内
PNMA2 Q9UL42 PRPF31 Homo sapiens Q8WWY3 25416956
种属内
PNMA2 Q9UL42 LRR1 Homo sapiens Q96L50 25416956
种属内
PNMA2 Q9UL42 LRR1 Homo sapiens Q96L50 25416956
种属内
PNMA2 Q9UL42 RPL9 Homo sapiens P32969 25416956
种属内
PNMA2 Q9UL42 PSMA1 Homo sapiens P25786 25416956
种属内
PNMA2 Q9UL42 RNF8 Homo sapiens O76064 25416956
种属内
PNMA2 Q9UL42 RNF8 Homo sapiens O76064 25416956
种属内
PNMA2 Q9UL42 RNF8 Homo sapiens O76064 25416956
种属内
PNMA2 Q9UL42 TOP3B Homo sapiens O95985 25416956
种属内
PNMA2 Q9UL42 PPIG Homo sapiens Q13427 25416956
种属内
PNMA2 Q9UL42 MORF4L2 Homo sapiens Q15014 25416956
种属内
PNMA2 Q9UL42 MORF4L2 Homo sapiens Q15014 25416956
种属内
PNMA2 Q9UL42 MORF4L2 Homo sapiens Q15014 25416956
种属内
PNMA2 Q9UL42 ZNF587 Homo sapiens Q96SQ5 25416956
种属内
PNMA2 Q9UL42 ZNF587 Homo sapiens Q96SQ5 25416956
种属内
PNMA2 Q9UL42 ZNF587 Homo sapiens Q96SQ5 25416956
种属内
PNMA2 Q9UL42 CBX8 Homo sapiens Q9HC52 25416956
种属内
PNMA2 Q9UL42 CBX8 Homo sapiens Q9HC52 25416956
种属内
PNMA2 Q9UL42 FAM161A Homo sapiens Q3B820 33961781
种属内
PNMA2 Q9UL42 SDCBP Homo sapiens O00560 25416956
种属内
PNMA2 Q9UL42 SDCBP Homo sapiens O00560 25416956
种属内
PNMA2 Q9UL42 ZNF417 Homo sapiens Q8TAU3 25416956
种属内
PNMA2 Q9UL42 ZNF417 Homo sapiens Q8TAU3 25416956
种属内
PNMA2 Q9UL42 ZNF417 Homo sapiens Q8TAU3 25416956
种属内
PNMA2 Q9UL42 ZNF417 Homo sapiens Q8TAU3
Y2H
21516116
种属内
PNMA2 Q9UL42 ENKD1 Homo sapiens Q9H0I2 25416956
种属内
PNMA2 Q9UL42 ENKD1 Homo sapiens Q9H0I2 33961781
种属内
PNMA2 Q9UL42 ENKD1 Homo sapiens Q9H0I2 25416956
种属内
PNMA2 Q9UL42 SCNM1 Homo sapiens Q9BWG6 25416956
种属内
PNMA2 Q9UL42 SCNM1 Homo sapiens Q9BWG6 25416956
种属内
PNMA2 Q9UL42 TTLL10 Homo sapiens Q6ZVT0 25416956
种属内
PNMA2 Q9UL42 TTLL10 Homo sapiens Q6ZVT0 25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Limbic Encephalitis
Autoimmune Epilepsy
Anterograde Amnesia

Amnesia, Anterograde

Encephalitis

Mumps Encephalitis

Mumps Meningoencephalitis

Herpes Simplex Neuroinvasion

Herpetic Encephalitis

Herpetic Encephalopathy

Herpes Simplex Encephalitis, Myelitis Or Encephalomyelitis

Encephalitis Due To Herpesviridae

Encephalitis Due To Herpesvirus

Herpes Encephalitis

Herpesviral Encephalitis

Herpes Simplex Encephalitis

Hsv - [Herpes Simplex Virus] Encephalitis

Herpes Virus Encephalitis

Simian B Disease

Simian B Disorder

Encephalitis Nec

Idiopathic Encephalitis

Oculomotor Nerve Paralysis

Iii Nerve Palsy

Iiird Nerve Paralysis

Third Cranial Nerve Paralysis

Neurosarcoidosis

Cerebral Sarcoidosis

Kleine-Levin Hibernation Syndrome

Kleine-Levin Syndrome

Familial Kleine-Levin Syndrome

Kleine Levin Syndrome

Familial Hibernation Syndrome

Recurrent Hypersomnolence

Hypersomnia-Bulimia Syndrome

Retinitis Pigmentosa 34

RP34

Recurrent Hypersomnia

Primary Recurrent Hypersomnia

Hypersomnia Recurrent

Disorders Of Excessive Somnolence

Hypersomnia, Recurrent

Acute Disseminated Encephalomyelitis

Acute Disseminated Encephalitis

Adem

Ade

Encephalomyelitis Acute Disseminated

Encephalomyelitis, Acute Disseminated

Adem - [Acute Disseminated Encephalomyelitis]

Postinfectious Encephalitis

Postinfective Encephalitis

Secondary Encephalitis

La Crosse Encephalitis

California Encephalitis

California Virus Encephalitis

Neuroinvasive California Encephalitis Virus Infection

Californian Encephalitis

Encephalitis, California

California Meningoencephalitis

California Encephalitis Virus Infection

California Encephalitis Virus Infection Neuroinvasive Disease

California Meningoencephalitis Virus Disease

California Serogroup Virus Neuroinvasive Disease

California Viral Encephalitis

Ce - [California Encephalitis]

Lac - [La Crosse Encephalitis]

Whipple Disease

Intestinal Lipodystrophy

Whipple'S Disease

Intestinal Lipophagic Granulomatosis

Secondary Non-Tropical Sprue

Tropheryma Whippelii Infection

Whipples Disease

Stiff-Person Syndrome

SPS

Stiff-Man Syndrome

Stiff Man Syndrome

Stiff Person Syndrome

Moersch-Woltman Syndrome

Sms

Stiff-Trunk Syndrome

Morsch Woltman Syndrome

Stiff Person Syndrome And Related Disorders

Stiff Person Spectrum Disorder

Classic Stiff Person Syndrome

Classic Sps

Focal Stiff Limb Syndrome

Focal Stiff-Person Syndrome

Stiff Leg Syndrome

Progressive Encephalomyelitis With Rigidity

Small Intestine Neuroendocrine Neoplasm

Small Intestine Neuroendocrine Tumor

Neuroendocrine Tumor Of The Small Intestine

Net Of The Small Intestine

Neuroendocrine Neoplasm Of The Small Intestine

Neuroendocrine Tumor Of Small Bowel

Small Intestinal Neuroendocrine Neoplasm

Akinetic Mutism

Coma Vigilans

Lingual-Facial-Buccal Dyskinesia

Orofacial Dyskinesia

Oro-Facial Dyskinesia

Dyskinesias

Testicular Disease

Testicular Dysfunction

Testicular Diseases

Disorder Of Testis

Testis Disorder

Testicular Disorders

Lateral Medullary Syndrome

Posterior Inferior Cerebellar Artery Syndrome

Wallenberg Syndrome

Vertebral Artery Syndrome

Wallenberg'S Syndrome

Pica Syndrome

Autoimmune Disease Of Peripheral Nervous System
Miller Fisher Syndrome

Cranial Variant Of Gbs

Fisher'S Syndrome

Miller-Fisher Variant Of Guillain-Barre Syndrome

Miller-Fisher Syndrome

Cranial Variant Of Guillain-Barré Syndrome

Cranial Variant Of Guillain-Barre Syndrome

Fisher Syndrome

Third Cranial Nerve Disease

Disorder Of Oculomotor Nerve

Oculomotor Nerve Disorder

Oculomotor Nerve Paralysis

Third Cranial Nerve Disorder

Mutism
Wernicke Encephalopathy

Wernicke'S Encephalopathy

Wernicke'S Disease

Encephalopathy, Wernicke'S

Wernicke-Korsakoff Syndrome

Encephalopathy Due To Vitamin B1 Deficiency

Wernicke Disease

Wernicke Syndrome

Thymus Gland Disease

Disease Of Thymus Gland

Gummatous Syphilis
Spastic Hemiplegia

Spastic Hemiplegic Cerebral Palsy

Hemiplegic Cerebral Palsy

Congenital Hemiplegia

Hemiplegic Infantile Cerebral Palsy

Cerebral Palsy Spastic Hemiplegic

Spastic Hemiplegia Cerebral Palsy

Hemiplegia, Spastic

Small Intestine Benign Neoplasm

Neoplasm Of Small Intestine

Small Intestinal Neoplasm

Neoplasm Of The Small Intestine

Small Bowel Cancer

Small Intestine Cancer

Malignant Neoplasm Of Small Intestine, Unspecified

Malignant Tumour Of Small Bowel

Malignant Tumour Of Small Intestine

Primary Malignant Neoplasm Of Meckel Diverticulum

Viral Encephalitis

Epidemic Encephalitis

Encephalitis Viral

Encephalitis, Arbovirus

Arbovirus Encephalitis

Postviral Encephalitis Nos

Equine Encephalitis

Tick-Borne Encephalitis

Viral Encephalitis Transmitted By Tick

Mosquito-Borne Encephalitis

Acute Haemorrhagic Encephalitis

Acute Idiopathic Encephalitis

Chronic Viral Encephalitis

Endemic Encephalitis

Subacute Viral Encephalitis

Viral Haemorrhagic Encephalitis

Viral Nonepidemic Encephalitis

Nonepidemic Encephalitis

Thymus Cancer

Thymic Neoplasm

Thymic Tumor

Thymus Neoplasm

Thymus Neoplasms

Malignant Neoplasm Of Thymus

Neoplasm Of Thymus

Thymic Neoplasms

Thymoma, Familial

Thymic Carcinoma

Thymoma, Type C

Cancer Of Thymus

Malignant Tumour Of Thymus

Primary Malignant Neoplasm Of Thymus

Thymic Glandular Cancer

Thymus Gland Cancer

Internuclear Ophthalmoplegia

Ophthalmoplegia Internuclearis

Bielschowsky-Lutz-Cogan Syndrome

Ino - [Internuclear Ophthalmoplegia]

Lhermitte Syndrome

Mlf - [Medial Longitudinal Fasciculus] Syndrome

Internuclear Paralysis

Meningovascular Neurosyphilis
Neuromuscular Junction Disease

Neuromuscular Junction Diseases

Invasive Malignant Thymoma

Infiltrating Thymoma

Thymoma Malignant Invasive

Invasive Thymoma And Thymic Carcinoma

Fallopian Tube Serous Adenocarcinoma
Choreatic Disease

Chorea

Hereditary Chorea

Testicular Cancer

Testis Cancer

Testicular Carcinoma

Testicular Neoplasms

Malignant Neoplasm Of Testis

Childhood Neoplasm Of The Testis

Neoplasm Of Testis

Pediatric Testicular Neoplasm

Testicular Tumor

Testis Neoplasm

Testicular Tumors

Testicular Neoplasm

Testicular Malignant Germ Cell Tumor

Childhood Testicular Neoplasm

Carcinoma Of The Testis

Cancer Of Testis

Malignant Neoplasm Of Testis, Nos

Malignant Neoplasm Of Testis, Unspecified

Malignant Tumour Of Testis

Testicle Cancer

Primary Malignant Neoplasm Of Testis

Hyperekplexia

Hereditary Hyperekplexia

Kok Disease

Congenital Stiff Man Syndrome

Familial Startle Disease

Sthe

Stiff-Baby Syndrome

Hereditary Hyperexplexia

Startle Disease

Exaggerated Startle Reaction

Hyperexplexia Hereditary

Startle Disease, Familial

Startle Reaction, Exaggerated

Stiff-Man Syndrome, Congenital

Stiff-Person Syndrome, Congenital

Congenital Stiff-Man Syndrome

Congenital Stiff-Person Syndrome

Familial Hyperekplexia

Startle Syndrome

Stiff Baby Syndrome

Hyperekplexia, Hereditary

Stiff-Person Syndrome

Optic Nerve Disease

Optic Neuropathy

Disorder Of The Second Nerve

Optic Nerve Disorder

Optic Nerve

Abnormality Of The Optic Nerve

Optic Nerve Disorders

Neuropathy, Optic

Disorder Of The Optic Nerve

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris PNMA2 VGNC VGNC:44747
Bos taurus PNMA2 VGNC VGNC:33084
Mus musculus PNMA2 MGD MGI:2444129
Macaca mulatta PNMA2 VGNC VGNC:84102
Rattus norvegicus PNMA2 RGD RGD:1307266
Felis catus PNMA2 VGNC VGNC:79973