1. Gene
  2. RPL9 - ribosomal protein L9 Gene

RPL9 - ribosomal protein L9 Gene

中文名称:核糖体蛋白 L9

种属: Homo sapiens

同用名: L9; NPC-A-16

基因 ID: 6133 | 基因类型: protein coding

关于 RPL9

Cytogenetic location: 4p14 Genomic coordinates (GRCh38): 4:39,454,124-39,458,922 (from NCBI)

This gene has 15 transcripts (splice variants) and 172 orthologues. Ubiquitous expression in ovary (RPKM 1269.0), bone marrow (RPKM 646.0) and 25 other tissues.

功能概要

核糖体是催化蛋白质合成的细胞器,由一个小的 40S 亚基和一个大的 60S 亚基组成。这些亚基一起由 4 种 RNA 和大约 80 种结构不同的蛋白质组成。该基因编码的核糖体蛋白是 60S 亚基的一个组成部分。该蛋白属于核糖体蛋白 L6P 家族。它位于细胞质中。作为典型的编码核糖体蛋白的基因,该基因有多个经过处理的假基因分散在基因组中。可变剪接导致多个转录本变体。[RefSeq 提供,2016 年 2 月]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L6P family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

RPL9 基因产物(2)

mRNA Protein Name
NM_000661.5 NP_000652.2 60S ribosomal protein L9
NM_001024921.4 NP_001020092.1 60S ribosomal protein L9
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16189514 GOA
enables structural constituent of ribosome IDA
IDA: 通过直接分析推断
23636399 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of cytosolic large ribosomal subunit IDA
IDA: 通过直接分析推断
32669547 GOA
part of cytosolic large ribosomal subunit IPI
IPI: 通过物理相互作用推断
25901680 GOA
located in cytosolic ribosome IDA
IDA: 通过直接分析推断
23636399 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

RPL9 蛋白结构

Ribosomal_L6

Ribosomal_L6: Ribosomal protein L6 (12 - 87)

Ribosomal_L6

Ribosomal_L6: Ribosomal protein L6 (99 - 178)

  • 0
  • 100
  • 192 a.a.
蛋白主名 其他名称

60S ribosomal protein L9

large ribosomal subunit protein uL6

RPL9 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
RPL9 P32969 BICDL2 Homo sapiens A1A5D9
Y2H Prey Pooling
32296183
种属内
RPL9 P32969 BICDL2 Homo sapiens A1A5D9
Y2H Array
32296183
种属内
RPL9 P32969 FAM9B Homo sapiens Q8IZU0
Y2H Array
25416956
种属内
RPL9 P32969 FAM9B Homo sapiens Q8IZU0
Y2H Prey Pooling
25416956
种属内
RPL9 P32969 ZBTB14 Homo sapiens O43829
Validated Y2H
25416956
种属内
RPL9 P32969 ZBTB14 Homo sapiens O43829
Y2H Array
25416956
种属内
RPL9 P32969 CCDC184 Homo sapiens Q52MB2
Validated Y2H
32296183
种属内
RPL9 P32969 CCDC184 Homo sapiens Q52MB2
Y2H Array
32296183
种属内
RPL9 P32969 CCDC184 Homo sapiens Q52MB2
Y2H Prey Pooling
32296183
种属内
RPL9 P32969 SREK1IP1 Homo sapiens Q8N9Q2
Y2H Array
32296183
种属内
RPL9 P32969 SREK1IP1 Homo sapiens Q8N9Q2
Validated Y2H
32296183
种属内
RPL9 P32969 SREK1IP1 Homo sapiens Q8N9Q2
Y2H Prey Pooling
32296183
种属内
RPL9 P32969 PSTPIP1 Homo sapiens O43586
Y2H Prey Pooling
32296183
种属内
RPL9 P32969 PSTPIP1 Homo sapiens O43586
Y2H Array
32296183
种属内
RPL9 P32969 CTNNA3 Homo sapiens Q9UI47-2
Validated Y2H
32296183
种属内
RPL9 P32969 CTTN Homo sapiens Q14247-3
Y2H Array
32296183
种属内
RPL9 P32969 CTTN Homo sapiens Q14247-3
Validated Y2H
32296183
种属内
RPL9 P32969 CTTN Homo sapiens Q14247-3
Y2H Prey Pooling
32296183
种属内
RPL9 P32969 BACH2 Homo sapiens Q9BYV9
Y2H Array
32296183
种属内
RPL9 P32969 BACH2 Homo sapiens Q9BYV9
Y2H Prey Pooling
32296183
种属内
RPL9 P32969 BACH2 Homo sapiens Q9BYV9
Validated Y2H
32296183
种属内
RPL9 P32969 HMBOX1 Homo sapiens Q6NT76
Y2H Array
32296183
种属内
RPL9 P32969 HMBOX1 Homo sapiens Q6NT76
Y2H Prey Pooling
32296183
种属内
RPL9 P32969 HMBOX1 Homo sapiens Q6NT76
Validated Y2H
32296183
种属内
RPL9 P32969 PNMA2 Homo sapiens Q9UL42
Y2H Prey Pooling
32296183
种属内
RPL9 P32969 PNMA2 Homo sapiens Q9UL42
Validated Y2H
25416956
种属内
RPL9 P32969 PNMA2 Homo sapiens Q9UL42
Validated Y2H
32296183
种属内
RPL9 P32969 PNMA2 Homo sapiens Q9UL42
Y2H Array
32296183
种属内
RPL9 P32969 PNMA2 Homo sapiens Q9UL42
Y2H Prey Pooling
25416956
种属内
RPL9 P32969 VCP Homo sapiens P55072
Y2H Prey Pooling
25416956
种属内
RPL9 P32969 VCP Homo sapiens P55072
Y2H Prey Pooling
32296183
种属内
RPL9 P32969 VCP Homo sapiens P55072
Validated Y2H
32296183
种属内
RPL9 P32969 VCP Homo sapiens P55072
Validated Y2H
25416956
种属内
RPL9 P32969 VCP Homo sapiens P55072
Y2H Array
32296183
种属内
RPL9 P32969 VCP Homo sapiens P55072
Y2H Array
25416956
种属内
RPL9 P32969 SNRPF Homo sapiens P62306
Y2H Prey Pooling
32296183
种属内
RPL9 P32969 SNRPF Homo sapiens P62306
Y2H Array
32296183
种属内
RPL9 P32969 SNRPF Homo sapiens P62306
Validated Y2H
32296183
种属内
RPL9 P32969 SRSF3 Homo sapiens P84103
Y2H Prey Pooling
32296183
种属内
RPL9 P32969 SRSF3 Homo sapiens P84103
Y2H Array
32296183
种属内
RPL9 P32969 SRSF3 Homo sapiens P84103
Validated Y2H
32296183
种属内
RPL9 P32969 PPP1R27 Homo sapiens Q86WC6
Y2H Array
32296183
种属内
RPL9 P32969 PPP1R27 Homo sapiens Q86WC6
Y2H Prey Pooling
32296183
种属内
RPL9 P32969 PPP1R27 Homo sapiens Q86WC6
Validated Y2H
32296183
种属内
RPL9 P32969 DRAP1 Homo sapiens Q14919
Validated Y2H
32296183
种属内
RPL9 P32969 DRAP1 Homo sapiens Q14919
Y2H Prey Pooling
32296183
种属内
RPL9 P32969 DRAP1 Homo sapiens Q14919
Y2H Array
32296183
种属内
RPL9 P32969 KXD1 Homo sapiens Q9BQD3
Validated Y2H
25416956
种属内
RPL9 P32969 ZBTB7B Homo sapiens O15156
Validated Y2H
25416956
种属内
RPL9 P32969 TIFA Homo sapiens Q96CG3
Y2H Prey Pooling
25416956
种属内
RPL9 P32969 TIFA Homo sapiens Q96CG3
Validated Y2H
25416956
种属内
RPL9 P32969 TIFA Homo sapiens Q96CG3
Y2H Prey Pooling
32296183
种属内
RPL9 P32969 TIFA Homo sapiens Q96CG3
Validated Y2H
32296183
种属内
RPL9 P32969 TIFA Homo sapiens Q96CG3
Y2H Array
32296183
种属内
RPL9 P32969 TRIM37 Homo sapiens O94972
Validated Y2H
25416956
种属内
RPL9 P32969 TRIM37 Homo sapiens O94972
Y2H Array
25416956
种属内
RPL9 P32969 TRIM37 Homo sapiens O94972
Y2H Prey Pooling
25416956
种属内
RPL9 P32969 CBY2 Homo sapiens Q8NA61
Y2H Array
25416956
种属内
RPL9 P32969 DHPS Homo sapiens P49366
Y2H Array
32296183
种属内
RPL9 P32969 DHPS Homo sapiens P49366
Anti Tag CoIP
33961781
种属内
RPL9 P32969 DHPS Homo sapiens P49366
Anti Tag CoIP
28514442
种属内
RPL9 P32969 DHPS Homo sapiens P49366
Y2H Prey Pooling
32296183
种属内
RPL9 P32969 DHPS Homo sapiens P49366
Y2H Prey Pooling
25416956
种属内
RPL9 P32969 DHPS Homo sapiens P49366
Validated Y2H
32296183
种属内
RPL9 P32969 ZBTB8A Homo sapiens Q96BR9
Y2H Array
32296183
种属内
RPL9 P32969 ZBTB8A Homo sapiens Q96BR9
Y2H Prey Pooling
25416956
种属内
RPL9 P32969 ZBTB8A Homo sapiens Q96BR9
Y2H Prey Pooling
32296183
种属内
RPL9 P32969 ZBTB8A Homo sapiens Q96BR9
Validated Y2H
32296183
种属内
RPL9 P32969 CEP76 Homo sapiens Q8TAP6
Validated Y2H
32296183
种属内
RPL9 P32969 CEP76 Homo sapiens Q8TAP6
Y2H Prey Pooling
32296183
种属内
RPL9 P32969 CEP76 Homo sapiens Q8TAP6
Y2H Array
32296183
种属内
RPL9 P32969 CEP76 Homo sapiens Q8TAP6
Anti Tag CoIP
33961781
种属内
RPL9 P32969 CEP76 Homo sapiens Q8TAP6
Anti Tag CoIP
28514442
种属内
RPL9 P32969 MTUS2 Homo sapiens Q5JR59
Y2H Prey Pooling
25416956
种属内
RPL9 P32969 STAC3 Homo sapiens Q96MF2
Y2H Prey Pooling
32296183
种属内
RPL9 P32969 STAC3 Homo sapiens Q96MF2
Y2H Array
32296183
种属内
RPL9 P32969 STAC3 Homo sapiens Q96MF2
Validated Y2H
32296183
种属内
RPL9 P32969 TNFAIP8L1 Homo sapiens Q8WVP5
Y2H Prey Pooling
32296183
种属内
RPL9 P32969 TNFAIP8L1 Homo sapiens Q8WVP5
Validated Y2H
32296183
种属内
RPL9 P32969 TNFAIP8L1 Homo sapiens Q8WVP5
Y2H Array
32296183
种属内
RPL9 P32969 RALY Homo sapiens Q53GL6
Y2H Prey Pooling
32296183
种属内
RPL9 P32969 RALY Homo sapiens Q53GL6
Validated Y2H
32296183
种属内
RPL9 P32969 RALY Homo sapiens Q53GL6
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Diamond-Blackfan Anemia 6

DBA6

Aase-Smith Syndrome Ii

Aase Syndrome

Aase Smith Syndrome 2

Rpl5-Related Diamond-Blackfan Anemia

Anemia, Diamond-Blackfan, Type 6

Diamond-Blackfan Anemia 1

Diamond-Blackfan Anemia 2

DBA2

Anemia, Diamond-Blackfan, 2

Anemia Diamond-Blackfan 2

Diamond-Blackfan Anemia

Congenital Pure Red Cell Aplasia

Aase Syndrome

Erythrogenesis Imperfecta

Anemia, Diamond-Blackfan

Congenital Hypoplastic Anemia

Aase-Smith Ii Syndrome

Bds

Blackfan-Diamond Anemia

Congenital Prca

Congenital Hypoplastic Anemia, Blackfan-Diamond Type

Dba

Blackfan - Diamond Syndrome

Chronic Constitutional Pure Red Cell Anaemia

Anemia Diamond Blackfan Type

Anemia Congenital Erythroid Hypoplastic

Aregenerative Anemia Chronic Congenital

Blackfan Diamond Syndrome

Red Cell Aplasia, Pure Hereditary

Aase-Smith Syndrome Ii

Bda

Blackfan Diamond Anemia

Blackfan-Diamond Disease

Blackfan-Diamond Syndrome

Chronic Congenital Agenerative Anemia

Congenital Erythroid Hypoplastic Anemia

Congenital Hypoplastic Anemia Of Blackfan And Diamond

Congenital Pure Red Cell Anemia

Hypoplastic Congenital Anemia

Inherited Erythroblastopenia

Pure Hereditary Red Cell Aplasia

Anemia, Hypoplastic, Congenital

Anemia Hypoplastic Congenital

Fanconi Anemia

Constitutional Aplastic Anemia

Diamond-Blackfan Anemia 1

Aase Smith Syndrome 2

Congenital Red Cell Aplasia

Red Cell Aplasia Of Infants

Pure Red Cell Aplasia Of Infants

Congenital Red Cell Aplastic Anaemia

Congenital Pure Red Cell Anaemia

Congenital Erythroid Hypoplasia

Pearson Marrow-Pancreas Syndrome

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus RPL9 RGD RGD:62049
Mus musculus RPL9 MGD MGI:1298373
Felis catus RPL9 VGNC VGNC:79993
Macaca mulatta RPL9 VGNC VGNC:107196
Canis familiaris RPL9 VGNC VGNC:53205