1. Gene
  2. CD300C - CD300c molecule Gene

CD300C - CD300c molecule Gene

中文名称:CD300c 分子

种属: Homo sapiens

同用名: LIR; CLM-6; CMRF35; IGSF16; CMRF-35; CMRF35A; CMRF-35A; CMRF35A1; CMRF35-A1

基因 ID: 10871 | 基因类型: protein coding

关于 CD300C

Cytogenetic location: 17q25.1 Genomic coordinates (GRCh38): 17:74,534,635-74,546,115 (from NCBI)

This gene has 1 transcript (splice variant), 157 orthologues and 13 paralogues. Broad expression in lung (RPKM 2.9), appendix (RPKM 2.6) and 19 other tissues.

功能概要

通过与单克隆抗体的反应性鉴定的 CMRF35 抗原存在于单核细胞、中性粒细胞和一些 T 和 B 淋巴细胞上 (Jackson 等人,1992 [PubMed 1349532]) 。[OMIM 提供,2008 年 3 月]

The CMRF35 antigen, which was identified by reactivity with a monoclonal antibody, is present on monocytes, neutrophils, and some T and B lymphocytes (Jackson et al., 1992 [PubMed 1349532]).[supplied by OMIM, Mar 2008]

CD300C 基因产物(1)

mRNA Protein Name
NM_006678.5 NP_006669.1 CMRF35-like molecule 6 precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
20959446 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

CD300C 蛋白结构

V-set

V-set: Immunoglobulin V-set domain (27 - 119)

  • 0
  • 100
  • 200
  • 224 a.a.
蛋白主名 其他名称

CMRF35-like molecule 6

CD300 antigen-like family member C

CD300C 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
CD300C Q08708 GPR151 Homo sapiens Q8TDV0
Y2H Prey Pooling
32296183
种属内
CD300C Q08708 GPR151 Homo sapiens Q8TDV0
Validated Y2H
32296183
种属内
CD300C Q08708 GPR151 Homo sapiens Q8TDV0
Y2H Array
32296183
种属内
CD300C Q08708 UNC93A Homo sapiens Q86WB7-2
Validated Y2H
32296183
种属内
CD300C Q08708 UNC93A Homo sapiens Q86WB7-2
Y2H Array
32296183
种属内
CD300C Q08708 UNC93A Homo sapiens Q86WB7-2
Y2H Prey Pooling
32296183
种属内
CD300C Q08708 TMEM167B Homo sapiens Q9NRX6
Y2H Prey Pooling
32296183
种属内
CD300C Q08708 TMEM167B Homo sapiens Q9NRX6
Validated Y2H
32296183
种属内
CD300C Q08708 TMEM167B Homo sapiens Q9NRX6
Y2H Array
32296183
种属内
CD300C Q08708 GPR42 Homo sapiens O15529
Y2H Prey Pooling
32296183
种属内
CD300C Q08708 GPR42 Homo sapiens O15529
Y2H Array
32296183
种属内
CD300C Q08708 FAM210B Homo sapiens Q96KR6
Validated Y2H
32296183
种属内
CD300C Q08708 FAM210B Homo sapiens Q96KR6
Y2H Array
32296183
种属内
CD300C Q08708 FAM210B Homo sapiens Q96KR6
Y2H Prey Pooling
32296183
种属内
CD300C Q08708 CD300LB Homo sapiens A8K4G0
Anti Tag CoIP
20959446
种属内
CD300C Q08708 LEPROTL1 Homo sapiens O95214
Y2H Array
32296183
种属内
CD300C Q08708 LEPROTL1 Homo sapiens O95214
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 CD300C 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76222 CD300c Protein, Human (HEK293, His) Q08708/NP_006669.1 (M29-R183) ≥95%

关联疾病

疾病名称 别名
Gastroduodenal Crohn'S Disease

Upper Gi Crohn'S Disease

Paget'S Disease Of Bone

Osteitis Deformans

Paget Disease Of Bone

Osseous Paget'S Disease

Paget Disease Of Bone, Familial

Bone Paget Disease

Familial Paget'S Disease Of Bone

Paget'S Bone Disease

Familial Paget Disease Of Bone

Paget Disease, Bone

Pdb

Pagets Bone Disease

Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis 1

FTDALS1

Frontotemporal Dementia And/Or Motor Neuron Disease

Ftdmnd

Amyotrophic Lateral Sclerosis And/Or Frontotemporal Dementia

Alsftd

Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis

Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis-1

Frontotemporal Dementia With Motor Neuron Disease

Ftdals

Ftd-Als

Ftd-Mnd

Frontotemporal Dementia With Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis With Frontotemporal Dementia 1

Amyotrophic Lateral Sclerosis/Frontotemporal Dementia

Dementia, Frontotemporal, And/Or Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis And/Or Frontotemporal Dementia 1

Frontotemporal Lobar Degeneration

Grn-Related Frontotemporal Dementia

Zellweger Syndrome

Cerebrohepatorenal Syndrome

Zellweger Leukodystrophy

Zs

Congenital Iron Overload

Chr

Zws

Severe Pbd-Zsd

Severe Peroxisome Biogenesis Disorder-Zellweger Spectrum Disorder

Amyotrophic Lateral Sclerosis 1

Amyotrophic Lateral Sclerosis

ALS

Lou Gehrig Disease

Amyotrophic Lateral Sclerosis Type 1

Charcot Disease

ALS1

Amyotrophic Lateral Sclerosis, Susceptibility To

Fals

Lou Gehrig'S Disease

Mnd

Motor Neuron Disease

Familial Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis 1, Familial

Amyotrophic Lateral Sclerosis 1, Autosomal Dominant

Motor Neuron Disease, Bulbar

Motor Neurone Disease

Amyotrophic Lateral Sclerosis With Dementia

Dementia With Amyotrophic Lateral Sclerosis

Motor Neuron Disease, Amyotrophic Lateral Sclerosis

Sclerosis, Lateral, Amyotrophic

Sclerosis, Lateral, Amyotrophic, Type 1

Amyotrophic Sclerosis

Als - [Amyotrophic Lateral Sclerosis]

Wasting Palsy

Amyotrophic Paralysis

Amyotrophy Lateral Sclerosis

Wasting Paralysis

Spinal Progressive Amyotrophy

Progressive Atrophic Paralysis

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta CD300C VGNC VGNC:99134
Rattus norvegicus CD300C RGD RGD:1565161
Others CD300C NCBI