NMU - neuromedin U Gene

中文名称：神经调节素 U

种属: Homo sapiens

关于 NMU

功能概要

该基因编码神经肽神经调节蛋白家族的成员。编码的蛋白质是一种前体，经过蛋白水解处理后可生成具有生物活性的神经肽，该神经肽在疼痛、压力、免疫介导的炎症性疾病和摄食调节中发挥作用。在肾癌、胰腺癌和肺癌中观察到该基因表达增加。可变剪接导致编码不同异构体的多个转录变体。这些同种型中的一些可能会经历类似的处理以生成成熟肽。[RefSeq 提供，2015 年 7 月]

This gene encodes a member of the neuromedin family of neuropeptides. The encoded protein is a precursor that is proteolytically processed to generate a biologically active neuropeptide that plays a role in pain, stress, immune-mediated inflammatory diseases and feeding regulation. Increased expression of this gene was observed in renal, pancreatic and lung cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. Some of these isoforms may undergo similar processing to generate the mature peptide. [provided by RefSeq, Jul 2015]