1. Gene
  2. SAT2 - spermidine/spermine N1-acetyltransferase family member 2 Gene

SAT2 - spermidine/spermine N1-acetyltransferase family member 2 Gene

中文名称:亚精胺/精胺 N1-乙酰转移酶家族成员 2

种属: Homo sapiens

同用名: SSAT2; SSAT-2

基因 ID: 112483 | 基因类型: protein coding

关于 SAT2

Cytogenetic location: 17p13.1 Genomic coordinates (GRCh38): 17:7,626,234-7,627,876 (from NCBI)

This gene has 14 transcripts (splice variants), 98 orthologues and 2 paralogues. Ubiquitous expression in kidney (RPKM 97.2), duodenum (RPKM 89.6) and 25 other tissues.

功能概要

启用二胺 N-乙酰转移酶活性和相同的蛋白质结合活性。参与多胺代谢过程。位于细胞外外泌体。 [由基因组资源联盟提供,2022 年 4 月]

Enables diamine N-acetyltransferase activity and identical protein binding activity. Involved in polyamine metabolic process. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

SAT2 基因产物(4)

mRNA Protein Name
NM_001320845.1 NP_001307774.1 thialysine N-epsilon-acetyltransferase isoform 1
NM_001320846.1 NP_001307775.1 thialysine N-epsilon-acetyltransferase isoform 2
NM_001320847.2 NP_001307776.1 thialysine N-epsilon-acetyltransferase isoform 4
NM_133491.5 NP_597998.1 thialysine N-epsilon-acetyltransferase isoform 3
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables N-acetyltransferase activity IDA
IDA: 通过直接分析推断
15283699 GOA
NOT enables diamine N-acetyltransferase activity IDA
IDA: 通过直接分析推断
15283699 GOA
enables diamine N-acetyltransferase activity IDA
IDA: 通过直接分析推断
12803540 GOA
enables identical protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
16189514 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in nor-spermidine metabolic process IDA
IDA: 通过直接分析推断
12803540 GOA
NOT involved in polyamine biosynthetic process IDA
IDA: 通过直接分析推断
15283699 GOA
involved in putrescine acetylation IDA
IDA: 通过直接分析推断
12803540 GOA
NOT involved in spermidine acetylation IDA
IDA: 通过直接分析推断
15283699 GOA
involved in spermidine acetylation IDA
IDA: 通过直接分析推断
12803540 GOA
involved in spermine acetylation IDA
IDA: 通过直接分析推断
12803540 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

SAT2 蛋白结构

Acetyltransf_1

Acetyltransf_1: Acetyltransferase (GNAT) family (70 - 145)

  • 0
  • 100
  • 170 a.a.
蛋白主名 其他名称

thialysine N-epsilon-acetyltransferase

diamine N-acetyltransferase 2

SAT2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
SAT2 Q96F10 SAT1 Homo sapiens P21673
Y2H Array
32296183
种属内
SAT2 Q96F10 SAT1 Homo sapiens P21673
Anti Tag CoIP
33961781
种属内
SAT2 Q96F10 SAT1 Homo sapiens P21673
Y2H Prey Pooling
32296183
种属内
SAT2 Q96F10 SAT2 Homo sapiens Q96F10
Y2H Array
31515488
种属内
SAT2 Q96F10 POTEF Homo sapiens A5A3E0
Anti Tag CoIP
33961781
种属内
SAT2 Q96F10 PANK2 Homo sapiens Q9BZ23
Anti Tag CoIP
33961781
种属内
SAT2 Q96F10 SAT2 Homo sapiens Q96F10
Validated Y2H
32296183
种属内
SAT2 Q96F10 PANK2 Homo sapiens Q9BZ23-3
Anti Tag CoIP
28514442
种属内
SAT2 Q96F10 SAT2 Homo sapiens Q96F10
Y2H Array
32296183
种属内
SAT2 Q96F10 RYBP Homo sapiens Q8N488
TAP
24981860
种属内
SAT2 Q96F10 C1QBP Homo sapiens Q07021
Crosslink
30021884
种属内
SAT2 Q96F10 SAT2 Homo sapiens Q96F10
Y2H Array
25416956
种属内
SAT2 Q96F10 H1-2 Homo sapiens P16403
TAP
24981860
种属内
SAT2 Q96F10 NDUFA10 Homo sapiens O95299
Crosslink
30021884
种属内
SAT2 Q96F10 SMR3B Homo sapiens P02814
TAP
24981860
种属内
SAT2 Q96F10 SAT2 Homo sapiens Q96F10
Y2H Prey Pooling
32296183
种属内
SAT2 Q96F10 SMC1A Homo sapiens Q14683
Crosslink
30021884
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Felis catus SAT2 VGNC VGNC:99444
Macaca mulatta SAT2 VGNC VGNC:77086
Bos taurus SAT2 VGNC VGNC:34297
Canis familiaris SAT2 VGNC VGNC:45874
Mus musculus SAT2 MGD MGI:1916465
Rattus norvegicus SAT2 RGD RGD:1307869
Others SAT2 NCBI