2. Gene
  3. Abi1 - abl interactor 1 Gene

Abi1 - abl interactor 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: E3B1; NAP1; abi-1; Ssh3bp1

基因 ID: 11308 | 基因类型: protein coding

关于 Abi1

功能概要

Enables protein tyrosine kinase activator activity and signaling adaptor activity. Acts upstream of or within megakaryocyte development; plasma membrane bounded cell projection morphogenesis; and somitogenesis. Located in lamellipodium and neuron projection. Part of SCAR complex. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and hemolymphoid system gland. Orthologous to human ABI1 (abl interactor 1). [provided by Alliance of Genome Resources, Apr 2022]

Abi1 基因产物(12)

mRNA Protein Name
NM_001077190.3 NP_001070658.1 abl interactor 1 isoform 1
NM_001077192.3 NP_001070660.1 abl interactor 1 isoform 4
NM_001077193.3 NP_001070661.1 abl interactor 1 isoform 5
NM_001331043.1 NP_001317972.1 abl interactor 1 isoform 6
NM_001331044.1 NP_001317973.1 abl interactor 1 isoform 7
NM_001331045.1 NP_001317974.1 abl interactor 1 isoform 8
NM_001377510.1 NP_001364439.1 abl interactor 1 isoform 9
NM_001377511.1 NP_001364440.1 abl interactor 1 isoform 10
NM_001377512.1 NP_001364441.1 abl interactor 1 isoform 11
NM_001377513.1 NP_001364442.1 abl interactor 1 isoform 12
NM_007380.4 NP_031406.2 abl interactor 1 isoform 3
NM_145994.3 NP_666106.1 abl interactor 1 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
9010225 MGI
enables protein tyrosine kinase activator activity IDA
IDA: 通过直接分析推断
12672821 MGI
enables signaling adaptor activity IDA
IDA: 通过直接分析推断
12672821 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within dendrite morphogenesis IDA
IDA: 通过直接分析推断
25297099 MGI
acts upstream of or within lamellipodium morphogenesis IMP
IMP: 通过突变表型推断
17664349 MGI
acts upstream of or within megakaryocyte development IMP
IMP: 通过突变表型推断
17664349 MGI
acts upstream of or within somitogenesis IMP
IMP: 通过突变表型推断
15755804 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of SCAR complex IDA
IDA: 通过直接分析推断
12672821 MGI
located in cell leading edge IDA
IDA: 通过直接分析推断
16831833 MGI
located in lamellipodium IDA
IDA: 通过直接分析推断
12672821 MGI
located in neuron projection IDA
IDA: 通过直接分析推断
21795692 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

abl interactor 1

abelson interactor 1

ablphilin-1

eps8 SH3 domain-binding protein

eps8 binding protein

spectrin SH3 domain binding protein 1

Abi1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Abi1 Q8CBW3 Eps8 Mus musculus Q08509
CoIP
9010225
种属内
Abi1 Q8CBW3 Sos2 Mus musculus Q02384
Affinity Chrom
11003655
种属内
Abi1 Q8CBW3 Wasf2 Mus musculus Q8BH43
Anti Bait CoIP
18044991
种属内
Abi1 Q8CBW3 Wasf2 Mus musculus Q8BH43
Pull Down
20697350
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00098 ABI1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Abi1 NCBI NCBI:10006
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